Results 111 to 120 of about 384,620 (341)
Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts [PDF]
Rho is a major small GTP-binding protein that is involved in the regulation of various cell functions, including proliferation and cell migration, through activation of multiple signaling molecules in various types of cells.
Kurose, Hitoshi +4 more
core +2 more sources
Background While treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL change.
Austin Barry +16 more
wiley +1 more source
Simvastatin inhibits TLR8 signaling in primary human monocytes and spontaneous TNF production from rheumatoid synovial membrane cultures [PDF]
Simvastatin has been shown to have anti-inflammatory effects that are independent of its serum cholesterol lowering action, but the mechanisms by which these anti-inflammatory effects are mediated have not been elucidated.
A Gierut +48 more
core +1 more source
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source
Rheumatoid arthritis-associated rheumatoid factors post-COVID-19
ObjectiveRheumatoid factors (RFs) are a hallmark of rheumatoid arthritis but also arise in infections, including COVID-19. Moreover, infections, again including COVID-19, are associated with rheumatoid arthritis development, positioning RFs as a ...
Adam H. Titi +8 more
doaj +1 more source
Clinical Significance of the Rheumatoid Serum Factor [PDF]
Jan Kellgren
openalex +1 more source
Emerging patterns of genetic overlap across autoimmune disorders. [PDF]
Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A +1 more
core +1 more source
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England +9 more
wiley +1 more source
Evaluation of VDRL test in Patients Rheumatoid arthritis [PDF]
Background and Aim: Rheumatoid arthritis is a systemic, chronic and inflammatory disease. It is characterized by the symmetric synovitis of the articules of the extremities.
AR Salehi Nodeh +3 more
doaj +1 more source

