Results 141 to 150 of about 315,994 (289)

Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis [PDF]

, 2010
© 2010 Cascão et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
AF Mourao, AK Andersson, Ana F Mourão, Ana M Rodrigues, BW Kirkham, C Gabay, DY Chen, Elsa Vieira-Sousa, ER Vossenaar, FA Houssiau, FC Arnett, G Parsonage, H Kokkonen, Helena Canhão, Henrique S Rosário, HJ Kim, IC Chikanza, Inês Perpétuo, J Cedergren, J Duarte, J Pene, JE Fonseca, JE Fonseca, JF Fries, Joaquim Polido-Pereira, João E Fonseca, K Nagatani, L Petrovic-Rackov, LA Joosten, LK Assi, LK Stamp, Luis Graca, M al-Janadi, M Chabaud, M Pelletier, Maria M Souto-Carneiro, ML Prevoo, Mário V Queiroz, P Barrera, P Weinmann, P Youinou, PE Poubelle, R Cascao, R Cascao, R Segal, RA Moura, Rita A Moura, Rita Cascão, S Kotake, SC Liang, TJ Smeets   +50 more
core   +3 more sources

Supervariate Gel Transforms into Various Biominerals in Salt Solutions

Advanced Functional Materials, EarlyView.
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang, Chong Wang, Yuk‐Tong Cheng, Junda Shen, Yunchen Long, Hongkun Li, Jie Yan, Yang Ren, Xiao Ma, Yufeng Huang, Zhengtao Xu, Jian Lu, Yang Yang Li   +12 more
wiley   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Effect of one week of yoga on function and severity in rheumatoid arthritis

BMC Research Notes, 2011
Background Previous studies have shown that yoga practice improved the hand grip strength in patients with rheumatoid arthritis (RA). Findings Sixty-four participants with RA (group average age ± S.D., 46.5 ± 9.6 years; 47 females) were assessed at the ...
Gaur Vaishali, Naveen Kalkuni V, Telles Shirley, Balkrishna Acharya   +3 more
doaj   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source

Making homes more accessible for people with mobility impairment: A lived experience perspective

Australian Journal of Social Issues, Volume 57, Issue 4, Page 956-969, December 2022., 2022
Abstract People with mobility impairment have the right to live in accessible housing that meets their needs. Although the Australian National Construction Code for residential housing will be amended to include minimum accessibility standards in September 2022, some states have chosen not to adopt these standards (New South Wales, Western Australia ...
Isabella Goodwin, Elise Davis, Di Winkler, Jacinta Douglas, Cornelia Wellecke, Kate D’Cruz, Peter Mulherin, Stephanie Liddicoat   +7 more
wiley   +1 more source

Analysis of Humira, Electro-Acupuncture, and Pulsatile Dry Cupping on Reducing Joint Inflammation in Patients with Rheumatoid Arthritis [PDF]

, 2015
Humira, an anti-TNF drug aimed at decreasing inflammation in Rheumatoid Arthritis patients, can cause skin diseases from rashes to skin cancer. Humira works by blocking the chemical receptor RANKL which inhibits the production of osteoclasts. Osteoclasts
Noll, Natalie
core   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source