Results 141 to 150 of about 4,504,355 (205)
Hydroxyapatite‐Coated Ti6Al4V With Liposome‐Encapsulated Gooseberry Extract for Orthopedic Applications
Journal of Biomedical Materials Research Part A, Volume 114, Issue 10, October 2026.Schematic illustration of gooseberry extract encapsulation in liposomes, loading onto hydroxyapatite‐coated Ti6Al4V, and subsequent evaluation of drug release, osteoblast response, osteosarcoma cell response, antibacterial activity, and bone healing. ABSTRACT
This study investigates gooseberry (Phyllanthus emblica) extract (GB) as a bioactive additive ...Bryson White, Susmita Bosewiley +1 more sourceMorpho‐Anatomical and HPTLC Investigations of Lysimachia nummularia L. (Primulaceae) Grown in Switzerland
Microscopy Research and Technique, Volume 89, Issue 10, Page 1230-1243, October 2026.This research provides a complete morphoanatomical description of Lysimachia nummularia, as well as a HPTLC profile. Standard techniques of light and scanning electron microscopies, as well as standard techniques of HPTLC, were used. ABSTRACT
Primulaceae are distributed all over the world, encompassing around 2590 species.Carolina Sabedotti, João Vitor da Costa Batista, Bettina Leonhard, Konrad Urech, Mahsa Ahmadinezhad, Jakob Maier, Stephan Baumgartner, Fabio Boylan, Carla Holandino, Jane Manfron +9 morewiley +1 more sourceDNA Origami Uptake in Y‐79 Retinoblastoma Cells Driven by Oligolysine Coating
Small Structures, Volume 7, Issue 10, October 2026.We show that polymeric coating can enable DNA origami nanoparticle internalization into ocular retinoblastoma cells. Not only are the coated nanoparticles well‐tolerable to the cells, but they also remain mobile in the vitreous of a porcine ex vivo model.Anna Klose, Zahra Gounani, Sergei Raik, Artturi Koivuniemi, Sonja Korhonen, Mika Reinisalo, Tatu Lajunen, Veikko Linko, Timo Laaksonen +8 morewiley +1 more sourceRosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice
British Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.Background and Purpose
Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott +6 morewiley +1 more sourceFrailty and Fitness in Older Adults With Acute Myeloid Leukemia: From Chronological Age to Multiparametric Assessment
European Journal of Haematology, Volume 117, Issue 4, Page 787-798, October 2026.ABSTRACT
Acute Myeloid Leukemia predominantly affects older adults, who often present with comorbidities, functional impairment, and frailty, limiting eligibility for intensive chemotherapy or allogeneic transplantation. Historically, treatment options were restricted to hypomethylating agents, low‐dose cytarabine, hydroxyurea, or supportive care, with Antonella Bruzzese, Enrica Antonia Martino, Santino Caserta, Maria Eugenia Alvaro, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Ernesto Vigna, Massimo Gentile +11 morewiley +1 more sourceAutoantibodies Serum Level and 10-Year Risk of Fractures Evaluated by FRAX® Tool in Rheumatoid Arthritis Patients
Open Access Rheumatology: Research and ReviewsRim Sghiri,1,* Hana Ben Hassine,2,* Mariam Ghozzi,2 Nejla El Amri,3 Khadija Baccouche,3 Rihab Sarraj,3 Zahid Shakoor,1 Adel Almogren,1 Elyes Bouajina3 1Immunology Unit, Department of Pathology, College of Medicine, King Saud University, Riyadh ...Sghiri R, Ben Hassine H, Ghozzi M, El Amri N, Baccouche K, Sarraj R, Shakoor Z, Almogren A, Bouajina E +8 moredoaj The mediating role of genes in the influence of intestinal flora on type 2 diabetes and the screening of diagnostic markers
Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1816-1834, October 2026.Using Mendelian randomization, TWAS/eQTL analysis, machine learning, and single‐cell RNA sequencing, this study identified gut microbiota taxa causally linked to type 2 diabetes, candidate mediator genes, and diagnostic markers (BEND7, BLVRA, C1orf85, and LAMC1).Yu‐yang Chen, Yi‐fan Shi, Xin‐yue Zhang, Jing‐yue Zhang, Shi‐mao Zhang, Heng‐xia Zhao, De‐liang Liu +6 morewiley +1 more sourceA Genetic Risk Variant Associated With the Risk of Primary Biliary Cholangitis Is Inherited From Neanderthals
Liver International, Volume 46, Issue 10, October 2026.ABSTRACT Background
Primary Biliary Cholangitis (PBC) is an autoimmune cholangiopathy with polygenic architecture and unknown aetiology. Evidence links Neanderthal‐derived genetic variants to autoimmune conditions; however, their contribution to PBC susceptibility remains unexplored.Alessio Gerussi, Chiara Caime, Harold Wang, Heather J. Cordell, George F. Mells, Richard N. Sandford, David E. Jones, Gideon Hirschfield, Katherine A. Siminovitch, M. Eric Gershwin, Brian D. Juran, Elizabeth J. Atkinson, Angela Cheung, Mariza de Andrade, Aris Baras, Konstantinos N. Lazaridis, Rosanna Asselta, Pietro Invernizzi, Manuela Sironi, Sriram Sankararaman, Canadian‐US PBC Consortium, UK‐PBC Consortium, James J. Fryett, Rebecca Darlay, Steven Flack, Ann Spicer, Victoria L. Mulcahy, Richard Sturgess, Christopher Healey, Andrew Yeoman, Anton Vj Gunasekera, Paul Kooner, Kapil Kapur, V. Sathyanarayana, Yiannis Kallis, Javaid Subhani, Rory Harvey, Roger McCorry, Paul Rooney, David Ramanaden, Richard Evans, Thiriloganathan Mathialahan, Jaber Gasem, Christopher Shorrock, Mahesh Bhalme, Paul Southern, Jeremy A. Tibble, David A. Gorard, Susan Jones, Brijesh Srivastava, Matthew R. Foxton, Carole E. Collins, David Elphick, Mazn Karmo, Francisco Porras‐Perez, Michael Mendall, Tom Yapp, Minesh Patel, Roland Ede, Joanne Sayer, James Jupp, Neil Fisher, Martyn J. Carter, Konrad Koss, Jayshri Shah, Andrzej Piotrowicz, Glyn Scott, Charles Grimley, Ian R. Gooding, Simon Williams, Judith Tidbury, Guan Lim, Kuldeep Cheent, Sass Levi, Dina Mansour, Matilda Beckley, Coral Hollywood, Terry Wong, Richard Marley, John Ramage, Harriet M. Gordon, Jo Ridpath, Theodore Ngatchu, Vijay Paul Bob Grover, Ray G. Shidrawi, George Abouda, L. Corless, Mark Narain, Ian Rees, Ashley Brown, Simon Taylor‐Robinson, Joy Wilkins, Leonie Grellier, Paul Banim, Debasish Das, Michael A. Heneghan, Howard Curtis, Helen C. Matthews, Faiyaz Mohammed, Mark Aldersley, Raj Srirajaskanthan, Giles Walker, Alistair McNair, Amar Sharif, Sambit Sen, George Bird, Martin I. Prince, Geeta Prasad, Paul Kitchen, Adrian Barnardo, Chirag Oza, Nurani N. Sivaramakrishnan, Prakash Gupta, Amir Shah, Chris Dj Evans, Subrata Saha, Katharine Pollock, Peter Bramley, Ashis Mukhopadhya, Stephen T. Barclay, Natasha McDonald, Andrew J. Bathgate, Kelvin Palmer, John F. Dillon, Simon M. Rushbrook, Robert Przemioslo, Chris McDonald, Andrew Millar, Cheh Tai, Stephen Mitchell, Jane Metcalf, Syed Shaukat, Mary Ninkovic, Udi Shmueli, Andrew Davis, Asifabbas Naqvi, Tom Jw Lee, Stephen Ryder, Jane Collier, Howard Klass, Matthew E. Cramp, Nichols Sharer, Richard Aspinall, Deb Ghosh, Andrew C. Douds, Jonathan Booth, Earl Williams, Hyder Hussaini, John Christie, Steven Mann, Douglas Thorburn, Aileen Marshall, Imran Patanwala, Aftab Ala, Julia Maltby, Ray Matthew, Chris Corbett, Sam Vyas, Saket Singhal, Dermot Gleeson, Sharat Misra, Jeff Butterworth, Keith George, Tim Harding, Andrew Douglass, Harriet Mitchison, Simon Panter, Jeremy Shearman, Gary Bray, Michael Roberts, Graham Butcher, Daniel Forton, Zahid Mahmood, Matthew Cowan, Debashis Das, Chin Lye Ch'ng, Mesbah Rahman, Gregory C. A. Whatley, Emma Wesley, Aditya Mandal, Sanjiv Jain, Stephen P. Pereira, Mark Wright, Palak Trivedi, Fiona H. Gordon, Esther Unitt, Altaf Palejwala, Andrew Austin, Vishwaraj Vemala, Allister Grant, Andrew D. Higham, Alison Brind, Ray Mathew, Mark Cox, Subramaniam Ramakrishnan, Alistair King, Simon Whalley, Jocelyn Fraser, S. J. Thomson, Andrew Bell, Voi Shim Wong, Richard Kia, Ian Gee, Richard Keld, Rupert Ransford, James Gotto, Charles Millson, Italian PBC Genetics Study Group, Andrea Affronti, Maurizia Brunetto, Barbara Coco, Giancarlo Spinzi, Gianfranco Elia, Carlo Ferrari, Ana Lleo, Luigi Muratori, Paolo Muratori, Piero Portincasa, Agostino Colli, Savino Bruno, Guido Colloredo, Francesco Azzaroli, Pietro Andreone, MariaConsiglia Bragazzi, Domenico Alvaro, Vincenzo Cardinale, Nora Cazzagon, Annarosa Floreani, Cristina Rigamonti, Floriano Rosina, Marco Carbone, Laura Cristoferi, Marco Festa, Eugenia Nofit, Miki Scaravaglio, Daphne D'Amato, Federica Malinverno, Pietro Lampertico, Francesca Donato, Stefano Fagiuoli, Piero L. Almasio, Edoardo Giannini, Carmela Cursaro, Massimo Colombo, Luca Valenti, Luca Miele, Angelo Andriulli, Grazia A. Niro, Ignazio Grattagliano, Lorenzo Morini, Giovanni Casella, Maria Vinci, Pier Maria Battezzati, Andrea Crosignani, Massimo Zuin, Alberto Mattalia, Vincenza Calvaruso, Silvia Colombo, Antonio Benedetti, Marco Marzioni, Andrea Galli, Fabio Marra, Mirko Tarocchi, Antonio Picciotto, Filomena Morisco, Luca Fabris, Lory Saveria Crocè, Claudio Tiribelli, Pierluigi Toniutto, Mario Strazzabosco +269 morewiley +1 more source
