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Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part II-Guidelines on Oral and Ocular Treatments. [PDF]
AllergyABSTRACT Background
Oral and ocular medications are frequently used in the treatment of allergic rhinitis (AR). As part of the update of the Allergic Rhinitis and its Impact on Asthma (ARIA)‐EAACI guidelines, this manuscript presents the ARIA‐EAACI 2024–2025 recommendations for oral and ocular treatments.Vieira RJ, Sousa-Pinto B, Bousquet J, Schünemann HJ, Zuberbier T, Bognanni A, Togias A, Samolinski B, Valiulis A, Williams S, Bedbrook A, Czarlewski W, Torres MJ, Shamji MH, Morais-Almeida M, Canonica GW, Vecillas LL, Dykewicz MS, Jacomelli C, Klimek L, Leemann L, Lourenço O, Papadopoulos NG, Pereira AM, Savouré M, Toppila-Salmi SK, Ventura MT, Yepes-Nuñez JJ, Cruz AA, Ciprandi G, Gemicioglu B, Giovannini M, Gradauskiene B, Jartti T, Jeseňák M, Kuna P, Kvedariene V, Larenas-Linnemann DE, Latiff AHA, Mohammad Y, Ohta K, Mahesh PA, Pali-Schöll I, Pfaar O, Regateiro FS, Roche N, Taborda-Barata L, Ulrik CS, Viegi G, Zhang L, Haahtela T, Cherrez-Ojeda I, Ivancevich JC, Khaltaev N, Yorgancioglu A, Abdullah B, Al-Ahmad M, Al-Nesf MA, Amaral R, Asllani J, Bergmann KC, Bernstein JA, Blaiss MS, Toskala E, Carreiro-Martins P, Casale T, Cecchi L, Fiocchi A, Giuliano AFM, Christoff G, Cirule I, de Sousa JC, Costa EM, Devillier P, Hossny E, Iinuma T, Ispayeva Z, Julge K, Kaidashev I, Bennoor KS, Kraxner H, Kull I, Kulus M, Kupczyk M, Kurchenko A, La Grutta S, Miculinic N, Tuyet LLT, Lee SM, Montefort S, Moreira A, Mullol J, Nadif R, Nakonechna A, Neffen HE, Niedoszytko M, O'Hehir RE, Ogulur I, Okamoto Y, Olze H, Palomares O, Panzner P, Patella V, Pitsios C, Puggioni F, Quirce S, Ramonaité A, Repka-Ramirez MS, Roberts G, Robles-Velasco K, Rottem M, Salapatas M, Sastre J, Scichilone N, Sisul JC, Solé D, Soto-Martinez ME, Sova M, Tantilipikorn P, Todo-Bom A, Tsaryk V, Tsiligianni I, Urrutia-Pereira M, Valovirta E, Vasankari T, Wallace D, Wang Y, Worm M, Yusuf OM, Gil-Mata S, Marques-Cruz M, Mahboub B, Romano A, Aberer W, Artesani MC, Azzolini E, Barreto B, Bartra J, Becker S, Beghe B, Boner A, Borowiack E, Bouchard J, Brussino L, Buhl R, Catamerò F, Charpin D, Chavannes NH, Chełmińska M, Cheng L, Chkhartishvili E, Cho SH, Chong-Neto HJ, Chu DK, Cingi C, Compalati E, Costa RA, Cvetkovski B, Cardona V, D'Amato G, Davies JM, Di Bona D, Gonzalez Diaz SN, Dimou MV, Doulaptsi M, Ferreira-da-Silva R, Gawlik R, Calvo-Gil M, Gómez MR, Gotua M, Grigoreas C, Guzman MA, House R, Hyland M, Ierodiakonou D, Karavelia A, Keith P, Kisiel M, Kosak TS, Kosnik M, Koyuncu IV, Kritikos V, Litynska J, Lombardi C, Louis G, Luo X, Martini M, Meço C, Mesonjesi E, Mihaltan F, Moniuszko M, Naclerio RN, Neisinger S, Ollert M, Ordak M, Paoletti G, Parmelli E, Perdomo-Flores EA, Pereira H, Pérez JMF, Pham-Thi N, Prokopakis E, Ribeiro-Vaz I, Rolla G, Romantowski J, Rombaux P, Rouadi PW, Ryan D, Sadowska E, Sakurai D, Salameh L, Serrano E, Da Silva J, Soyka MB, Specjalski K, Tomic-Spiric V, Stevanovic K, Subramaniam A, Thomander T, Tong W, Vachova M, van Hage M, Wagenmann M, Ko FWS, Werminghaus P, Xepapadaki PV, Xiang YK, Yang Q, Zhang H, Zuberbier J, Fonseca JA. +230 moreeuropepmc +2 more sourcesTrends in Asthma-Rhinitis Allergic Multimorbidity and Polysensitization in China: The CARRAD Study. [PDF]
MedComm (2020)This cross‐sectional study highlights the increasing prevalence of allergic diseases and comorbidities under environmental conditions of rapid modernization in China. Our observations underline the relevance of the allergic comorbidities phenotype at the clinical and public health levels.Wang W, Wang J, Song G, Xie H, Zhu R, He Y, Tang J, Wang J, Yang J, Zhi L, Wu L, Jiang Y, Zhou X, Huang D, Wang N, Xu R, Gao Y, Chen Z, Han X, Tan G, Wu J, Zhao D, Chen J, Zhang W, Sun Y, Jiang Y, Zhang W, Qiu Q, Liu C, Yin J, Hao G, Li H, Xu Y, Chen S, Chen S, Meng J, Zeng D, Tang W, Hao C, Zhong N, Li J, China Alliance of Research on Respiratory Allergic Disease (CARRAD). +41 moreeuropepmc +2 more sourcesPerennial allergic rhinitis and keratoconjunctivitis [PDF]
Thorax, 2000 There are many studies dedicated to the allergic nose, but most of them deal with seasonal allergic rhinitis and particularly with acute experimental situations. Perennial allergic rhinitis is less well documented. When studying the allergic nose, several aspects must be taken into consideration: the genetic background of the patient, various ...openaire +2 more sourcesThe role of H2 antagonists in perennial allergic rhinitis [PDF]
The Laryngoscope, 1993 AbstractThe biological effects of anti‐H2 in allergic reactions are dose dependent: low doses enhance, and high doses significantly decrease the reaction of hypersensitivity. The administration of cimetidine H2 antagonist to 20 perennial allergic rhinitis patients brought about an abatement in the symptoms and a decrease in the total serum ...TESTA B, MESOLELLA C, FILIPPINI, Pietro, CAMPAGNANO N, TESTA, Domenico, MESOLELLA M, SAGNELLI E. +6 moreopenaire +4 more sourcesOlfactory dysfunction in seasonal and perennial allergic rhinitis
Acta Oto-Laryngologica, 2012 The limitation in olfactory function in patients with seasonal allergic rhinitis (AR) can be ascribed to an increase in eosinophilic and mast cell activity in the olfactory cleft. Therefore, the decrease in olfactory functions seems to be predominantly caused by the inflammation of the epithelium and not by the obstruction of the nose caused by the ...Becker, Sven, Pflugbeil, Claus, Groeger, Moritz, Canis, Martin, Ledderose, Georg J., Kramer, Matthias F. +5 moreopenaire +3 more sourcesExhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis
Allergy, EarlyView.Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes +9 morewiley +1 more sourceTreatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis
Allergy, EarlyView.ABSTRACT Background
To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.Bernardo Sousa‐Pinto, Rafael José Vieira, Sara Gil‐Mata, Ana Margarida Pereira, Vítor Henrique Duarte, Antonio Bognanni, Manuel Marques‐Cruz, Paweł Jemioło, Mattia Giovannini, Danilo di Bona, Arnav Agarwal, Mark S. Dykewicz, Mohamed H. Shamji, Maria Jose Torres, Torsten Zuberbier, Ludger Klimek, Alexandro W. L. Chu, Holger J. Schünemann, Guido Schwarzer, João A. Fonseca, Jean Bousquet, on behalf of the ARIA 2024–2025 systematic reviews group, Ana Teixeira‐Ferreira, André Ferreira, António Cardoso‐Fernandes, Despo Ierodiakonou, Diana Portela, Ewa Borowiack, Ewelina Sadowska, Henrique Ferreira‐Cardoso, Hugo Viegas, Izabel Pera Calvi, João Castro‐Teles, José Laerte Boechat, Juliana Pereira‐Macedo, Maria Inês Torres, Marta Soares Pereira, Miguel Campos‐Lopes, Nuno Lourenço‐Silva, Pau Riera‐Serra, Paula Perestrelo, Raquel Albuquerque‐Costa, Renato Ferreira‐da‐Silva, Rita A. Silva Ribeiro, Tuuli Thomander +44 morewiley +1 more sourcePreventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children
Allergy, EarlyView.HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi +12 morewiley +1 more sourceEfficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial
Allergy, EarlyView.Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang +18 morewiley +1 more source
