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Pathophysiology of perennial allergic rhinitis
Allergy, 1997Allergic rhinitis involves an early phase, largely mediated through mast cells, and a late phase which involves cellular infiltration and mediator release. In the early phase, mast cells release mediators as a result of antigen crossâlinking adjacent immunoglobulin E molecules bound to mast cell surfaces.
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Perennial Allergic Rhinitis and Nasal Hyperreactivity
American Journal of Rhinology, 1998This article focuses on the nose as an accessible organ for research purposes, exploring whether the nose can be used to study lower airway processes.
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Efficacy of montelukast for treating perennial allergic rhinitis
Allergy and Asthma Proceedings, 2007Perennial allergic rhinitis (PAR) is a chronic inflammatory nasal condition in individuals exposed year-round to allergens. This was a double-blind study of 15- to 85-year-old patients randomly allocated to montelukast, 10 mg (n=630), placebo (n=613), or the positive control cetirizine, 10 mg (n=122) for 6 weeks.
George, Philip +8 more
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2018
Compared with seasonal allergic rhinitis (SAR), exposure to allergens on a year-around basis leads to persistent symptoms that can be associated with significant impairment of quality of life. As is the case with SAR, management of perennial allergic rhinitis (PAR) entails aeroallergen avoidance, pharmacotherapy, and in properly select cases allergen ...
Martin A. Smith, David M. Lang
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Compared with seasonal allergic rhinitis (SAR), exposure to allergens on a year-around basis leads to persistent symptoms that can be associated with significant impairment of quality of life. As is the case with SAR, management of perennial allergic rhinitis (PAR) entails aeroallergen avoidance, pharmacotherapy, and in properly select cases allergen ...
Martin A. Smith, David M. Lang
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Topical levocabastine for the treatment of perennial allergic rhinitis
The Journal of Laryngology & Otology, 1997AbstractThe ultrastructure of the nasal mucosa following theuse of intranasal levocabastine was studied in 20 patients suffering from perennial allergic rhinitis. The patients received twice daily 0.05 per cent levocabastine spray with a treatment duration of four weeks.
S, Elwany, M, Bassiouny
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Practice Nursing, 1998
The nose is the first part of the natural airway, a fact often forgotten by doctors and nurses alike. Airflow in the nose is rapid, and during a sniff it ean easily reach the speed of a hurricane! It draws in all the airborne pollutants and particles and filters most of them out of the inhaled air before they reach the sensitive lining of the lungs ...
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The nose is the first part of the natural airway, a fact often forgotten by doctors and nurses alike. Airflow in the nose is rapid, and during a sniff it ean easily reach the speed of a hurricane! It draws in all the airborne pollutants and particles and filters most of them out of the inhaled air before they reach the sensitive lining of the lungs ...
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Neuronal Plasticity in Persistent Perennial Allergic Rhinitis
Journal of Occupational and Environmental Medicine, 2005Persistent perennial allergic rhinitis belongs to the most frequent diseases in occupational and environmental medicine. Because the innervation may play a role in the pathogenesis of the disease, the present study analyzed nasal mucosal nerve profiles.Neuropeptide-containing nerve fibers were examined using immunohistochemistry and related to ...
Axel, Fischer +9 more
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Polymorphism of the CD14 gene in perennial allergic rhinitis
International Journal of Pediatric Otorhinolaryngology, 2006Allergic diseases have strong genetic backgrounds. Recently, a C-T polymorphism in the promoter region of CD14 has been associated with phenotypes of atopy in some populations. The aim of this study was to investigate the association of CD14/-159 polymorphism with total serum IgE levels and number of positive skin prick tests in Korean population with ...
Hee Joon, Kang +5 more
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The anticholinergic treatment of allergic perennial rhinitis
Journal of Allergy and Clinical Immunology, 1992Anticholinergic agents have been used for nonallergic rhinitis expressly to control rhinorrhea. In allergic rhinitis, rhinorrhea can be extremely troublesome and unresponsive to traditional pharmacotherapeutic rhinitis treatments. Anticholinergic agents, through their specific ability to decrease nasal secretory response, should have beneficial effects
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Bepotastine besilate for the treatment of perennial allergic rhinitis
Expert Opinion on Pharmacotherapy, 2018Bepotastine besilate (BB) is a second-generation H1-antihistamine that, as an ophthalmic solution, is approved in the United States by the Food and Drug Administration (FDA) for the treatment of allergic conjunctivitis. In other countries, the oral presentation of BB is widely used for the improvement of symptoms of allergic rhinitis (AR) as well as ...
Ismael, Carrillo-Martin +2 more
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