Results 111 to 120 of about 38,742 (257)

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh   +3 more
wiley   +1 more source

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Allergic rhinitis in patients with asthma: the Swiss LARA (Link Allergic Rhinitis in Asthma) survey

, 2009
OBJECTIVE: To determine the characteristics of asthma (A) and allergic rhinitis (AR) among asthma patients in primary care practice. RESEARCH DESIGN AND METHODS: Primary care physicians, pulmonologists, and allergologists were asked to recruit ...
Taegtmeyer, Anne B, Steurer-Stey, C., Taegtmeyer, A.B., Leuppi, J.D., Helbling, A., Helbling, A, Leuppi, Joerg D., Taegtmeyer, Anne B., Helbling, Arthur, Miedinger, David, Schafroth, Salome, Scherer, Kathrin, Spertini, F., Schafroth, S, Bircher, A., Scherer, K., Taegtmeyer, A B, Leuppi, J D, Scherer, K, Bircher, Andreas, Leuppi, Joerg D, Miedinger, D., Spertini, F, Steurer-Stey, Claudia, Schafroth, S., Steurer-Stey, C, Spertini, François, Bircher, A, Miedinger, D   +28 more
core   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source

Porcine circovirus 2 vaccination timing was not associated with piglets’ serological response

Veterinary Record, EarlyView.
Abstract Background The development of immunity in pigs starts in utero, but piglets are born immunologically immature and rely on maternal antibodies. Weaning exposes piglets to multiple stressors, yet vaccination is commonly performed around weaning.
Lea Uotinen, Sanna Nikunen, Gitte Blach Nielsen, Mari Heinonen   +3 more
wiley   +1 more source

Intranasal ciclesonide for allergic rhinitis

, 2008
Ben Williams, William B Smith, Frank E KetteDepartment of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, South AustraliaAbstract: Ciclesonide is a novel corticosteroid which is optimized for topical use.
Ben Williams, Frank E Kette, William B Smith   +2 more
core  

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source

Particulate Matter 2.5 and Respiratory Symptoms in Urban and Suburban Schoolchildren in Ho Chi Minh City, Vietnam

Journal of Health Science and Medical Research (JHSMR)
Objective: To document the pattern of particulate matter 2.5 (PM2.5) concentration in urban and suburban schools in Ho Chi Minh City (HCMC) and to estimate the prevalence of wheezing and rhinitis among schoolchildren according to sociodemographic ...
Huynh Ngoc Thanh, Pham Le An, Le Huynh Thi Cam Hong, Tran Ngoc Dang, Nguyen Lu Phuong, Do Thi Hoai Thuong, Phan Hoang Thuy Dung, Bui Minh Tri, Nguyen Minh Quoc, Huynh Vo Quang Kiet, Alan Frederick Geater   +10 more
doaj   +1 more source