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Mechanisms and pathogenesis of chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and is historically divided into two main phenotypes: CRS with nasal polyps (NPs) (CRSwNP) and CRS without NPs (CRSsNP).
A. Kato, R. Schleimer, B. Bleier
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Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with significant morbidity and reduced health‐related quality of life. Findings from clinical trials have demonstrated the effectiveness of dupilumab in CRSwNP, although real‐world evidence ...
E. de Corso +72 more
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European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012.
W. Fokkens +147 more
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Chronic Rhinosinusitis with Nasal Polyps: Quality of Life in the Biologics Era.
Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally divided into two main phenotypic subsets, based on the presence or absence of nasal polyps (CRSwNP and CRSsNP, respectively).
J. Mullol +4 more
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Upper airway obstruction in rhinitis and rhinosinusitis
Rhinosinusitis is one of the most common diseases of the upper airways. It affects more than 10 % of adults and 70 % of children. Rhinosinusitis is a frequent cause of work incapacitation.
Jitka Vydrová
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Maxillary Rhinosinusitis Profil In General Hospital Of Haji Surabaya On January-December 2017
Chronic rhinosinusitis in various countries in the world and Indonesia shows an increase from time to time. At General Hospital of Haji Surabaya, the prevalence of chronic rhinosinusitis has increased from 10.13% in 2016 to 10.26% in 2017.
Indra Setiawan
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Burden of Disease in Chronic Rhinosinusitis with Nasal Polyps
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammation-mediated disease of the nasal mucosa and paranasal sinuses with an under-recognized clinical, humanistic, and economic burden. Patients with CRSwNP experience a high
C. Bachert +3 more
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Current issues in the diagnostics of paediatric chronic rhinosinusitis [PDF]
Introduction and objective. Paediatric chronic rhinosinusitis (PCRS) is a common disease in children. It is defined as an ongoing inflammation of the nasal cavity and sinuses lasting for over 12 weeks.
Mielnik-Niedzielska, G. +7 more
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Nasal Nitric Oxide in Children: A Review of Current Outreach in Pediatric Respiratory Medicine
Nasal nitric oxide (nNO) is a gas synthesized by the inducible and constitutive NO synthase (NOS) enzyme in the airway cells of the nasal mucosa. Like lung nitric oxide, it is thought to be associated with airway inflammation in various respiratory ...
Iva Mrkić Kobal +2 more
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International consensus statement on allergy and rhinology: rhinosinusitis 2021
The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected
R. Orlandi +88 more
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