Results 81 to 90 of about 89,228 (352)

An Amalgamation of Triple Entity: A Rare Co-existence of Antrochoanal Polyp, Ethmoidal Polyp and Fungal Sinusitis [PDF]

Journal of Clinical and Diagnostic Research
The co-existence of Antrochoanal Polyp (ACP), ethmoidal polyposis, and fungal sinusitis presents a unique diagnostic and therapeutic challenge due to overlapping symptoms and distinct treatment approaches.
Parindita Sarmah, Sagar Gaurkar, Prasad Deshmukh, Shakti Sagar   +3 more
doaj   +1 more source

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32‐Week Randomized Phase 1b Multiple Ascending‐Dose Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh, Chaim M. Brickman, Peter Lloyd, Ashish Kalra, Subhabrata Biswas, Arkadeep Sinha, Alex Mulvanny, Sumathi Sivapalasingam, Oren M. Becker, Aaron Deykin   +9 more
wiley   +1 more source

Epidemiology and burden of nasal congestion [PDF]

, 2010
Nasal congestion, which may be described as fullness, obstruction, reduced airflow, or being "stuffed up," is a commonly encountered symptom in clinical practice. Systematic study of congestion has largely considered it as a component of a disease state.
Ferguson, BJ, Fromer, L, Stewart, M
core   +3 more sources

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Chronic sinusitis in children: A general overview

South African Family Practice, 2011
No abstract available.
R.L. Friedman
doaj   +1 more source

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]

, 2017
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen, Angus, Bannasch, Barrs, Beatty, Bennett, Berryessa, Bexfield, Binns, Bongrand, Boothe, Bradley, Burns, Chalker, Chalker, Chan, Chandler, Confalonieri, Danish Small Animal Veterinary Association (SvHKS), Dear, Demetriou, Demko, Dossin, Drawz, Egberink, Ellis, Erles, German, Guardabassi, Hartmann, Helps, Henderson, Hollis, Hunter, Jameson, Johnson, Johnson, Johnson, Johnson, Johnson, Keil, Kogan, Kompare, Lee, Lees, Levy, Lionel, Litster, MacPhail, Maggs, Martino, McInnis, McKiernan, Meijvis, Melendez, Meyers, Mochizuki, Morley, Mulholland, Murphy, Owen, Papich, Parnham, Peeters, Pesavento, Priestnall, Priestnall, Proulx, Pui-Ying, Quimby, Quimby, Radhakrishnan, Renshaw, Rheinwald, Rheinwald, Rooney, Rozanski, Ruch-Galle, Ruch-Gallie, Ruch-Gallie, Schulz, Schwarz, Sparkes, Speakman, Speakman, Spindel, Stillion, Sturgess, Sykes, Tart, Trow, Tynan, Vanderkooi, Veir, Velineni, Viitanen, Waddell, Walker, Welsh, Westfall, Wong, Zhu   +101 more
core   +4 more sources

Stratification of chronic rhinosinusitis with nasal polyps by distinct sinonasal microbial communities and their clinical and pathological correlations

iMetaOmics, EarlyView.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang, Yanmin Liu, Qing Bao, Lin Sun, Hexin Chen, Qingxiang Meng, Linyi Jiao, Xiaoyan Ye, Jian Li, Tao Ding, Chunwei Li   +10 more
wiley   +1 more source

The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps.

Rhinology, 2019
BACKGROUND Chronic rhinosinusitis (CRS) is a common yet under-recognised chronic inflammatory disease of the nose and paranasal sinuses that is classified according to the presence (CRSwNP) or absence (CRSsNP) of nasal polyps.
Asif H Khan, G. Vandeplas, T. Huynh, Vijay N. Joish, L. Mannent, P. Tomassen, T. Zele, L. Cardell, Julia Arebro, H. Olze, U. Foerster-Ruhrmann, M. L. Kowalski, A. Olszewska-Ziąber, G. Holtappels, N. D. Ruyck, C. V. Drunen, J. Mullol, P. Hellings, V. Hox, E. Toskala, G. Scadding, V. Lund, W. Fokkens, Claus Bachert   +23 more
semanticscholar   +1 more source

Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]

, 2013
Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y, Gane, S, Larco, J, Miller, B, Mirakian, R, Sannah, AA, Scadding, G   +6 more
core   +1 more source

The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next‐Generation Sequencing in Moderate‐to‐Severe Bronchiectasis

Journal of Clinical Laboratory Analysis, EarlyView.
This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li, Qiuping Quan, Junshan Chen, Xiaoyun Jian, Weijie Zhan, Jingmin Wang, Rongbin Jiang   +6 more
wiley   +1 more source