Results 261 to 270 of about 82,160 (288)
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Activation of the small GTP-binding proteins rho and rac by growth factor receptors

Journal of Cell Science, 1995
ABSTRACT The small GTP-binding proteins, rho and rac, control signal transduction pathways that link growth factor receptors to the activation of actin polymerization. In Swiss 3T3 cells, rho proteins mediate the lysophosphatidic acid and bombesin-induced formation of focal adhesions and actin stress fibres, whilst rac proteins are ...
Alan Hall   +3 more
openaire   +3 more sources

Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells

Canadian Journal of Physiology and Pharmacology, 1996
The actin cytoskeleton is involved in numerous cellular functions such as cell motility, mitogenesis, morphology, muscle contraction, cytokinesis, and establishment of cell polarity. The members of the Rho subfamily of small GTP-binding proteins emerge as key regulators of cytokeleton organization.
Diane Bilodeau   +2 more
openaire   +3 more sources

Control of reorganization of the actin cytoskeleton by Rho family small GTP-binding proteins in yeast

Current Opinion in Cell Biology, 1998
Accumulating evidence indicates that Rho family small GTP-binding proteins regulate reorganization of the actin cytoskeleton. There are members of the Rho family in the budding yeast Saccharomyces cerevisiae, in which powerful molecular genetical approaches are applicable.
Yoshimi Takai, Kazuma Tanaka
openaire   +2 more sources

The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach

Gene, 1992
Partial sequences corresponding to eleven novel Rab proteins and one new Rho protein have been isolated using a PCR-based cloning approach. These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells.
Marino Zerial   +2 more
openaire   +3 more sources

Signaling Pathways Controlled by Rho Family GTP-Binding Proteins

2000
The current Rho family picture contains 11 mammalian members, which can be subdivided into five groups on the basis of sequence and functional differences: (1) RhoA, RhoB, and RhoC; (2) Rac1, Rac2, and RhoG; (3) Cdc42 and TC10; (4) RhoD; and (5) RhoE and TTF (1,2).
openaire   +2 more sources

Modification of the GTP-binding RHO proteins byC. difficile toxin A and B

Pharmacological Research, 1995
Jörg Selzer   +3 more
openaire   +2 more sources

Nanooncology: The future of cancer diagnosis and therapy

Ca-A Cancer Journal for Clinicians, 2013
Avnesh S Thakor
exaly  

MicroRNAome genome: A treasure for cancer diagnosis and therapy

Ca-A Cancer Journal for Clinicians, 2014
Ioana Berindan-neagoe   +2 more
exaly  

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