An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang +3 more
wiley +1 more source
Highly Sensitive Measurement of the Refractive Index of Mesoporous Hollow Silica Microcapsules Using Whispering Gallery Mode Resonances. [PDF]
Xu Q +5 more
europepmc +1 more source
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Development of a green spectrofluorimetric method for mefenamic acid determination using Rhodamine 6G with mechanistic investigation and central composite design optimization. [PDF]
Alqahtani AS +5 more
europepmc +1 more source
Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li +9 more
wiley +1 more source
Synergistic effects of poly-silicon aluminum sulfate and auxiliary agents in dye wastewater decolorization. [PDF]
Min J +7 more
europepmc +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
Alternating isomerization of pseudo-rhodamine and its ultrafast electrochromic video display. [PDF]
Yao Z +5 more
europepmc +1 more source

