Results 241 to 250 of about 111,364 (320)

π‐PhenoDrug: A Comprehensive Deep Learning‐Based Pipeline for Phenotypic Drug Screening in High‐Content Analysis

open access: yesAdvanced Intelligent Systems, EarlyView.
This study develops a deep learning‐based pipeline named π‐PhenoDrug for cell phenotype‐driven drug activity screening. π‐PhenoDrug integrates cell segmentation, morphological profile construction, and phenotype analysis modules, and it can assess drug effects on living cells in both supervised and unsupervised modes.
Xiao Li   +7 more
wiley   +1 more source

Effects of Qingyangshen glycosides on neuroplasticity in a mouse model of social defeat

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Summary of the experimental effects of qingyangshen glycosides on neuroplasticity in mice model of social defeat. Abstract Background Qingyangshen (Cynanchum otophyllum C.K. Schneid) is a folk drug for treating depression and other mental disorders induced by social defeat stress.
Jingru Wang   +6 more
wiley   +1 more source

Endogenous hydrogen sulfide persulfidates endothelin type A receptor to inhibit pulmonary arterial smooth muscle cell proliferation. [PDF]

open access: yesRedox Biol
Zhang Y   +11 more
europepmc   +1 more source

Accelerated Cellular Senescence in Progressive Multiple Sclerosis: A Histopathological Study

open access: yesAnnals of Neurology, EarlyView.
Objective The neurodegenerative processes driving the build‐up of disability in progressive multiple sclerosis (P‐MS) have not been fully elucidated. Recent data link cellular senescence (CS) to neurodegeneration. We investigated for evidence of CS in P‐MS and sought to determine its pattern.
Dimitrios Papadopoulos   +8 more
wiley   +1 more source

The adsorption of rhodamine on to suspended sediments

open access: yesICES Journal of Marine Science, 1975
J. W. Talbot, Myrtle J. Boon
openaire   +2 more sources

Manipulation of Chemistry and Biology with Visible Light Using Tetra‐ortho‐Substituted Azobenzenes and Azonium Ions

open access: yesAngewandte Chemie, EarlyView.
Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano   +2 more
wiley   +2 more sources

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