Results 261 to 270 of about 111,364 (320)

Synthetic High‐Throughput Microarrays of Peptidoglycan Fragments as a Novel Sero‐Diagnostic Tool for Patient Antibody Profiling

open access: yesAngewandte Chemie International Edition, EarlyView.
Using a novel on‐chip synthesis technology, microarrays of peptidoglycan fragments were generated comprising 864 variants derived from Gram‐positive and Gram‐negative bacteria. These were used to map monoclonal antibody specificity and to screen samples from patients with the autoimmune disease epidermolysis bullosa, revealing distinct antibody ...
Alexandra Tsouka   +12 more
wiley   +1 more source

Chemical Proteomics Reveals Human Off‐Targets of Fluoroquinolone Induced Mitochondrial Toxicity

open access: yesAngewandte Chemie International Edition, EarlyView.
A schematic overview of the adverse effects of Ciprofloxacin related to mitochondrial toxicity. AIFM1 plays a role in the MIA40‐mediated import into the IMS and oxidative folding of nuclear‐encoded proteins, including ETC complexes I and IV subunits. Ciprofloxacin disrupts the IMS import machinery, impairing ETC function.
Till Reinhardt   +14 more
wiley   +1 more source

Recent progress in triplet energy transfer systems toward organic afterglow materials. [PDF]

open access: yesCommun Chem
Wu K   +8 more
europepmc   +1 more source

A Photoactivatable Plasma Membrane Probe Based on a Self‐Triggered Photooxidation Cascade for Live Cell Super‐Resolution Microscopy

open access: yesAngewandte Chemie International Edition, Accepted Article.
Super‐resolution imaging based on the localization of single emitters requires a spatio‐temporal control of the ON and OFF state. To this end, photoactivatable fluorophores are adapted as they can be turned on upon light irradiation. Here we present a concept called Self‐Triggered Photooxidation Cascade (STPC) based on the photooxidation of a plasma ...
Sonia Pfister   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy