Results 71 to 80 of about 113,431 (288)

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]

open access: yes, 2015
Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S.   +3 more
core   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

open access: yesAdvanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu   +7 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

open access: yesAdvanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao   +9 more
wiley   +1 more source

THQ–Xanthene: An Emerging Strategy to Create Next‐Generation NIR‐I/II Fluorophores

open access: yesAdvanced Science, 2023
Near‐infrared fluorescence imaging is vital for exploring the biological world. The short emissions (
Zhiqiang Mao   +6 more
doaj   +1 more source

Fluorescence of Supported Phospholipid Bilayers Recorded in a Conventional Horizontal-Beam Spectrofluorometer [PDF]

open access: yes, 2016
Supported phospholipid bilayers are a convenient model of cellular membranes in studies of membrane biophysics and protein-lipid interactions. Traditionally, supported lipid bilayers are formed on a flat surface of a glass slide to be observed through ...
Kovrigin, Evgeni L.   +1 more
core   +1 more source

Gold surface with gold nitride–a surface enhanced Raman scattering active substrate [PDF]

open access: yes, 2009
The nitration of gold surfaces is a nonpolluting method, which can lead to large scale production of substrates with remarkable properties and applications. We present a topographical study of the nanoscale structure of the gold nitride surfaces produced
Alves, Luis   +3 more
core   +2 more sources

3D Bioinspired Hair‐Based Solar Evaporator for Efficient Water Harvesting

open access: yesAdvanced Functional Materials, EarlyView.
A bio‐derived solar evaporator inspired by blackbody radiation is developed using human hair waste. The vertically aligned hair structure enables broadband light absorption, efficient thermal localization, and rapid water transport, achieving high evaporation rates and stable desalination performance.
Yi Liu   +10 more
wiley   +1 more source

Microwave-assisted synthesis of rhodamine derivatives

open access: yesGreen Chemistry Letters and Reviews, 2018
The microwave synthesis of 12 rhodamine-derived imines is described. The present work involves condensation of rhodamine hydrazide with various aromatic aldehydes in ethanol under microwave irradiation. The results obtained indicate that, unlike classical heating, microwave irradiation results in higher yields, shorter reaction time, mild reaction ...
Angela Winstead   +4 more
openaire   +4 more sources

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