Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Unexpected ventricular fibrillation triggered by pulsed field ablation for atrial fibrillation
Wael Zaher, MD +6 more
doaj +1 more source
Functional Substrate Mapping in Ablation for Scar-Related Ventricular Tachycardia. [PDF]
Nakahara S, Sato H, Bradfield JS.
europepmc +1 more source
Encoding Cumulation to Learn Perturbative Nonlinear Oscillatory Dynamics
Weak nonlinearities critically shape the long term behavior of oscillatory systems but are difficult to identify from data. A data‐driven framework is introduced to infer governing equations of weakly nonlinear oscillators from sparse and noisy observations.
Teng Ma +5 more
wiley +1 more source
Network meta-analysis of catheter ablation, rhythm control, and rate control strategies in atrial fibrillation with heart failure impact on mortality, cardiac function, and quality of life. [PDF]
Gao H +7 more
europepmc +1 more source
Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui +8 more
wiley +1 more source
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou +19 more
wiley +1 more source
Left Ventricular Summit Premature Ventricular Complex Ablation
Sharonjebamalar B +3 more
doaj +1 more source
Chrono-immunotherapy's current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits. [PDF]
Liu D, Li Z, Cui H, Zhang H, Li H, Wu X.
europepmc +1 more source

