Results 311 to 320 of about 1,236,122 (386)

Novel 4,5‐Dihydrothiazole‐phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

open access: yesChemMedChem, Accepted Article.
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi   +18 more
wiley   +1 more source

Nodal Rhythm

open access: bronze, 1934
B. T. Parsons-Smith
openalex   +1 more source

Using the HClO4–H2O2 System for Efficient Platinum Leaching: Optimal Conditions and Kinetics

open access: yesChemPlusChem, EarlyView.
GA: The platinum leaching using HClO4 and H2O2 is studied. For each HClO4 concentration, an H2O2/HClO4 = 2.5 ratio optimizes the kinetics. The best operating conditions are ≈70 °C, [HClO4] 3 m, and [H2O2] 7.2 m. The leaching process is governed by diffusion in the boundary layer and chemical reaction. In this new extraction process, Cl2(g) is generated
Anailda Alvarado‐Gómez   +4 more
wiley   +1 more source

Variety of sleep and circadian rhythms of elderly dementia patients living in group home residences. [PDF]

open access: yesBiogerontology
Kubota N   +7 more
europepmc   +1 more source

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen   +5 more
wiley   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Understanding Transient Left Ventricular Ejection Fraction Reduction During Atrial Fibrillation With Artificial Intelligence. [PDF]

open access: yesJ Am Heart Assoc
Yuan N   +8 more
europepmc   +1 more source

Modern and ancient tidal sedimentary systems in the era of energy transition: Introduction to the special volume of The Depositional Record

open access: yesThe Depositional Record, EarlyView.
This volume examines tidal sedimentary systems through 11 articles, spanning ancient and modern tidalites, technological advances and implications for human management. Highlighting contributions from Tidalites 2022 and beyond, it underscores tidalites' significance in sedimentology, environmental forecasting and energy transition, reflecting decades ...
Sergio G. Longhitano   +2 more
wiley   +1 more source

Feeding regime synchronizes circadian clock in choroid plexus - insight into a complex mechanism. [PDF]

open access: yesCell Mol Life Sci
Dočkal T   +5 more
europepmc   +1 more source

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