Results 291 to 300 of about 156,401 (384)

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

Proceedings of the National Academy of Sciences of the United States of America, 2002

semanticscholar   +1 more source

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Hoyeraal-Hreidarsson syndrome: a case report of dyskeratosis congenita with a novel PARN gene mutation. [PDF]

Ann Med Surg (Lond)
Çalişkan Kamiş Ş, Çil M, Yağci-Küpeli B.   +2 more
europepmc   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

The long non-coding RPPH1 is decreased in leukocytes and increased in plasma from women developing pre-eclampsia†. [PDF]

Biol Reprod
Myhrer DM, Frøystad M, Paasche Roland MC, Ueland T, Lekva T.   +4 more
europepmc   +1 more source

Ribonuclease E, an Intermediate in the Degradation of Ribonuclease by Porcine Elastase

, 1965
Werner A. Klee
openalex   +1 more source

Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract.

Kidney International, 2011
J. Spencer, A. Schwaderer, J. Dirosario, K. McHugh, Glen McGillivary, S. Justice, Ashley R. Carpenter, Peter B. Baker, J. Harder, D. Hains   +9 more
semanticscholar   +1 more source

Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Overcoming platinum resistance in high‐grade serous ovarian cancer (HGSOC) is critical for improving outcomes. This study identifies lncRNA CATED, elevated in platinum‐resistant small extracellular vesicles (sEVs) and tumors, which drives cisplatin resistance by enhancing DHX36 SUMOylation, boosting RAP1A translation, and activating MAPK signaling ...
Yi Liu, Hanyuan Liu, Chenchen Zhu, Yan Yang, Zhen Shen, Ge Shan, Liang Chen, Ying Zhou   +7 more
wiley   +1 more source

Adrenocorticotrophin and Adrenal Protein Synthesis [PDF]

, 1965
Reddy, W. J., Scriba, Peter Christian
core  

The Reaction of Iodoacetate with Ribonuclease-S

, 1961
Paul J. Vithayathil, Frederic M. Richards   +1 more
openalex   +1 more source