Results 341 to 350 of about 156,401 (384)

Ribonucleases and autophagy : ribonucleases as antitumoral agents

, 2015
Prats, Guillem,, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
openaire   +1 more source

Enzymatic characterization and dominant sites of foot-and-mouth disease virus 2C protein. [PDF]

Heliyon
Zhou S, Liu N, Tian Y, Pan H, Han Y, Li Z, Zhang J, Guan S, Chen H, Song Y.   +9 more
europepmc   +1 more source

Correction: DIS3 ribonuclease is essential for spermatogenesis and male fertility in mice.

Development
Wang Z, Wu D, Xu X, Yu G, Li N, Wang X, Li JL, Dean J.   +7 more
europepmc   +1 more source

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DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC).

Journal of the American Chemical Society, 2022
Ribonuclease targeting chimeras (RiboTACs) induce degradation of an RNA target by facilitating an interaction between an RNA and a ribonuclease (RNase). We describe the screening of a DNA-encoded library (DEL) to identify binders of monomeric RNase L to ...
Samantha M. Meyer, Toru Tanaka, Patrick R. A. Zanon, Jared T. Baisden, D. Abegg, Xueyi Yang, Yoshihiro Akahori, Zainab Alshakarchi, M. Cameron, A. Adibekian, M. Disney   +10 more
semanticscholar   +1 more source

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Biochemistry, 1979
Intact ribonucleic acid (RNA) has been prepared from tissues rich in ribonuclease such as the rat pancreas by efficient homogenization in a 4 M solution of the potent protein denaturant guanidinium thiocyanate plus 0.1 M 2-mercaptoethanol to break ...
J. Chirgwin, A. Przybyla, Raymond J MacDonald, W. Rutter   +3 more
semanticscholar   +1 more source

Ribonuclease and ribonuclease inhibitor in the human pancreas

Gastroenterologia Japonica, 1983
Previous investigations have failed to confirm any specificity of elevated serum ribonuclease (RNase) in the diagnosis of pancreatic cancer. Although RNase had been known to be present in two forms (free and inhibitor-bound) in various rat tissues, little was known about its presence in the human pancreas. This report investigates the presence of RNase
Matsutoshi Menjo, Hideyasu Kiyohara
openaire   +3 more sources

Ribonucleases

Current Protocols in Molecular Biology, 2008
AbstractRibonucleases (RNases) with different sequence or structural specificities are used for a variety of analytical purposes, including RNA sequencing, mapping, and quantitation. The development of RNase protection assays, structural determination assays, and the production of small interfering RNAs (siRNA) employed in RNA interference (RNAi ...
Dongxian Yue, Nicole M. Nichols
openaire   +3 more sources

Artificial ribonucleases

Org. Biomol. Chem., 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Teija, Niittymäki, Harri, Lönnberg
openaire   +2 more sources

Protein engineering of ribonucleases

Biochimie, 1998
Natural bovine seminal RNase possesses a potent antitumor action. We have mutagenized monomeric bovine pancreatic RNase A, devoid of any cytotoxic action, to insert residues present at corresponding positions in the subunit of dimeric, antitumor, seminal RNase.
CAFARO, VALERIA, BRACALE, AURORA, Formiggini F., NOTOMISTA, EUGENIO, D'ALESSIO, GIUSEPPE, DI DONATO, ALBERTO   +5 more
openaire   +7 more sources

Nitration of ribonuclease

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1968
Abstract The nitration of bovine pancreatic ribonuclease with tetranitromethane has been studied. A procedure involving solvent extraction of excess reagent and product is described. A spectrophotometric procedure for determining the extent of nitration of tyrosines has been devised, which is not vitiated by the presence of other chromophoric ...
Walter Gratzer, Walter Gratzer, G.H. Beaven, G.H. Beaven   +3 more
openaire   +3 more sources