Results 161 to 170 of about 10,117 (175)

Small nuclear ribonucleoprotein polypeptide B2 regulated by SNHG4/miR-204-5p axis inhibits ferroptosis to aggravate the progression of hepatocellular carcinoma. [PDF]

Discov Oncol
Guo J, Li L, Wang H, Gao Z, Shen C, Yan B.   +5 more
europepmc   +1 more source

Alternative Splicing: A Potential Therapeutic Target in Hematological Malignancies. [PDF]

Hematol Rep
Temaj G, Chichiarelli S, Saha S, Telkoparan-Akillilar P, Nuhii N, Hadziselimovic R, Saso L.   +6 more
europepmc   +1 more source

Splice site diversity and abundance of noncanonical introns in diplonemids (Diplonemea, Euglenozoa). [PDF]

RNA
Thakur PK, Butenko A, Karásek F, Svobodová M, Faktorová D, Pavlisková H, Varga V, Horák A, Lukeš J, Staněk D.   +9 more
europepmc   +1 more source

Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder

Greene D, Mendez R, Lees J, Barbosa M, Bruselles A, Chiriatti L, Mancini C, Undiagnosed Diseases Network, Bertini ES, Bonner DE, Cassini TA, Ezell KM, Gomez-Ospina N, Rives L, Shashi V, Spillmann RC, Wafik M, Tartaglia M, Bernstein JA, Mumford AD, Wheeler MT, Turro E.   +21 more
europepmc   +1 more source

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

Cell, 1985
Two different experimental approaches have provided evidence that both U2 and U1 snRNPs function in pre-mRNA splicing. When the U2 snRNPs in a nuclear extract are selectively degraded using ribonuclease H and either of two deoxyoligonucleotides complementary to U2 RNA, splicing activity is abolished. Mixing an extract in which U2 has been degraded with
D L, Black, B, Chabot, J A, Steitz
openaire   +2 more sources

Psoriasis and Raynaud's Phenomenon Associated with Autoantibodies to U1 and U2 Small Nuclear Ribonucleoproteins

New England Journal of Medicine, 1986
One of the hallmarks of systemic lupus erythematosus and related disorders is the production of antinuclear antibodies reactive with a variety of nuclear structures, including nucleic acids (DNA an...
W H, Reeves, D E, Fisher, R, Wisniewolski, A B, Gottlieb, N, Chiorazzi   +4 more
openaire   +2 more sources

Ribonucleoprotein particle assembly and modification of U2 small nuclear RNA containing 5-fluorouridine

Biochemistry, 1993
An in vitro assembly/modification system was used to study the effect of 5-fluorouridine (5-FU) incorporation on the biosynthesis of the U2 small nuclear ribonucleoprotein particle (U2 snRNP). Labeled U2 RNAs were transcribed in vitro with 5-fluoro-UTP either partially supplementing or completely replacing UTP during synthesis.
openaire   +2 more sources

Affinity Chromatography of Splicing Complexes: U2, U5, and U4 + U6 Small Nuclear Ribonucleoprotein Particles in the Spliceosome

Science, 1986
The splicing process, which removes intervening sequences from messenger RNA (mRNA) precursors is essential to gene expression in eukaryotic cells. This site-specific process requires precise sequence recognition at the boundaries of an intervening sequence, but the mechanism of this recognition is not understood.
P J, Grabowski, P A, Sharp
openaire   +2 more sources