Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas +3 more
wiley +1 more source
The Levels of Ribonucleotide Reductase, Thioredoxin, Glutaredoxin 1, and GSH Are Balanced in Escherichia coli K12 [PDF]
, 1996 Antonio Miranda–Vizuete +5 more
openalex +1 more source
Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.Substituting the bridging carboxylates in diFe sulerythrin shifts the bridging ligand coordination from 1,3‐carboxylate to 1,1‐carboxylate, yielding all three diferrous bridging motifs in one protein. This shortens the Fe–Fe distance and increases reactivity with O2.
Jae‐Hun Jeoung +6 more
wiley +1 more source
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
Nature Communications, 2019 DNA polymerases epsilon and delta, respectively, perform the majority of leading and lagging strand replication of the eukaryotic nuclear genome. Here the authors map the ribonucleotide fingerprints of the polymerases to show the special roles of ...
Zhi-Xiong Zhou +4 more
doaj +1 more source
The small subunit of ribonucleotide reductase is encoded by one of the most abundant translationally regulated maternal RNAs in clam and sea urchin eggs. [PDF]
, 1985 NANCY M. STANDART +4 more
openalex +1 more source
Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology [PDF]
, 1990 Four recombinant, diagnostically useful Epstein-Barr virus (EBV) proteins representative of the viral capsid antigen (p150), diffuse early antigen (p54), the major DNA-binding protein (p138), and the EBV nuclear antigen (p72) (W. Hinderer, H.
Gorgievski-Hrisoho, M. +7 more
core +1 more source
Broad Transgenic, and Cardiac-Specific Viral Mediated, Over-Expression of Ribonucleotide Reductase Increases In Vivo Cardiac Contractility [PDF]
, 2012 F. Steven Korte +10 more
openalex +1 more source
DNA methyltransferase inhibitors in hematological malignancies and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger +3 more
wiley +1 more source
Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase
, 2020 Clorice R. Reinhardt +5 more
openalex +2 more sources