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The Nature of Distribution of Ribonucleotide Reductases

1988
Ribonucleotide reductases catalyze the irreversible reduction of the 2’-hydroxyl group of ribonucleoside 5’-phosphates to the corresponding 2’-deoxyribonucleoside 5’-phosphates. This reaction is a prerequisite for DNA replication and thus controls the S phase of a cell cycle and cell proliferation.
Hartmut Follmann   +2 more
openaire   +2 more sources

Closing the circle on ribonucleotide reductases

Nature Structural & Molecular Biology, 2011
In this issue, a wide array of structural and biochemical techniques are applied to reveal the molecular details of activity regulation in one of life's most essential enzymes, the ribonucleotide reductase.
openaire   +2 more sources

Clinical pharmacology and clinical trials of ribonucleotide reductase inhibitors: is it a viable cancer therapy?

Journal of Cancer Research and Clinical Oncology, 2017
Mukundan Baskar Mannargudi, S. Deb
semanticscholar   +1 more source

Ribonucleotide Reductase

RCSB Protein Data Bank, 2019
D. Goodsell
semanticscholar   +1 more source

Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein.

Biochemical Pharmacology, 2016
Xia Liu   +13 more
semanticscholar   +1 more source

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