Results 281 to 290 of about 6,124,063 (361)
Jelena Jakovljevic +7 more
semanticscholar +1 more source
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang +14 more
wiley +1 more source
Decoding ribosome complexity: role of ribosomal proteins in cancer and disease. [PDF]
Fuentes P, Pelletier J, Gentilella A.
europepmc +1 more source
Scission of the p53-MDM2 Loop by Ribosomal Proteins.
Xiaoping Zhou +3 more
semanticscholar +1 more source
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen +16 more
wiley +1 more source
Single cell transcriptomics profiling of the stromal cells in the pathologic association of ribosomal proteins in the ischemic myocardium and epicardial fat. [PDF]
Thai A +10 more
europepmc +1 more source
Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang +13 more
wiley +1 more source

