Results 111 to 120 of about 173,360 (283)
The Plant Cell, 2019 The functional organization of ribosomal DNA and ribosome assembly in plants is described, along with recent findings concerning a plant-specific mechanism involved in ribosome stress responses.
J. Sáez-Vásquez, M. Delseny
semanticscholar +1 more source
Food Frontiers, EarlyView.Our results indicate that although high‐dose parenteral iron effectively corrects iron deficiency anemia (IDA), it causes liver dysfunction, immune suppression, systemic iron overload, and altered gut microbiota. ABSTRACT Iron deficiency anemia (IDA) is a common nutritional disorder in mammals, particularly affecting neonates and neonatal piglets ...
Qian Zhang +4 more
wiley +1 more source
Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment
Journal of Pharmaceutical AnalysisRibosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced functionality. Mutation or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ...
Mengxin Wang +9 more
doaj +1 more source
SMY2 and SYH1 suppress defects in ribosome biogenesis caused by ebp2 mutations [PDF]
, 2015 Akira Okano +5 more
openalex +1 more source
Regulation of Ribosome Biogenesis in Skeletal Muscle Hypertrophy.
Physiology, 2019 The ribosome is the enzymatic macromolecular machine responsible for protein synthesis. The rates of protein synthesis are primarily dependent on translational efficiency and capacity. Ribosome biogenesis has emerged as an important regulator of skeletal
V. Figueiredo, J. McCarthy
semanticscholar +1 more source
Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing
Advanced Genetics, EarlyView.This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley +1 more source
Suppressor mutations in Rpf2–Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation
Nature Communications, 2018 During biogenesis of the eukaryotic 60S ribosome, a large rotational movement of the 5S RNP is required to achieve its mature position. By analyzing extragenic suppressors of crg1—a key factor required for rotation—the authors provide mechanistic insight
Matthias Thoms +6 more
doaj +1 more source
Ribosome biogenesis and the cellular energy economy
Current Biology, 2022 D. Shore, B. Albert
semanticscholar +1 more source
Glia, EarlyView.SCZ astrocytes display an increased pro‐inflammatory profile upon TNF‐α stimulation. Reactive SCZ astrocytes induce microglial‐like cells to assume a dystrophic phenotype. Reactive SCZ astrocytes limit iMGs' synaptoneurosome uptake and migration. ABSTRACT Neuroinflammation, particularly astrocyte reactivity, is increasingly linked to schizophrenia (SCZ)
Pablo L. Cardozo +18 more
wiley +1 more source