Results 141 to 150 of about 35,431,844 (244)

Ribosome-inactivating proteins: Entry into mammalian cells and intracellular routing

To catalytically-modify ribosomes in vivo, ribosome-inactivating proteins produced by plants must enter susceptible mammalian cells in order to reach their substrates in the cytosol.

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RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley   +1 more source

Plant-Derived Anti-TMV Metabolites: Mechanisms, Limitations and Future Perspectives. [PDF]

Viruses
Aslam MQ, Gao Z, Mohamed AS, El-Sayed SM, Yang W, Cheng L, Wu K, Li Y, Chen Y.   +8 more
europepmc   +1 more source

Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease

MedComm, Volume 7, Issue 9, September 2026.
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi, Dongping Yao, Chanjuan Dong, Xiao Tu, Guojian Liao, Mengfei Long, Yongmei Xie   +6 more
wiley   +1 more source

The L-A dsRNA Virus and Its Satellites: Totiviruses and Killers in <i>Saccharomyces cerevisiae</i>. [PDF]

Viruses
Wickner RB, Edskes HK.
europepmc   +1 more source

Molecular insights and translational opportunities to enhance heat tolerance in rice

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana, Chanderkant Chaudhary, Rajat Pruthi, Mansi Sharma, Bhupinderjeet Singh, Ravi Kiran Reddy Kondi, Mallesham Bulle, Prasanta K. Subudhi   +7 more
wiley   +1 more source

<i>Panax ginseng</i> as a proteome-metabolome medicinal ecosystem: Reframing pharmacology beyond a strictly saponin-centric paradigm. [PDF]

J Ginseng Res
Yoo BC, Cho JY, Kim MY.
europepmc   +1 more source

Endogenous CRISPR‐Based Removal of Tetracycline Resistance in Bifidobacterium animalis subsp. lactis Through a Safe‐by‐Design Approach

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
Endogenous CRISPR–Cas editing was used to inactivate tetW gene in Bifidobacterium animalis subsp. lactis. The engineered strain showed reduced tetracycline resistance while retaining key probiotic traits and genetic stability. This work demonstrates a Safe‐by‐Design strategy for engineering safer industrial probiotics and mitigating antimicrobial ...
Marianna Bozzetti, Matteo Raneri, Claudia Cortimiglia, Giovanni Milani, Federica Volontè, Franco Lucchini, Daniela Bassi, Pier Sandro Cocconcelli   +7 more
wiley   +1 more source

Genetics of ribosome-inactivating proteins

Ribosome-inactivating proteins (RIPs) are a heterogeneous group of enzymes found mainly in plants and a few bacteria that possess N-glycosidase activity on ribosomes and a related polynucleotide adenosine glycosidase activity on naked nucleic acids. They

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Biophysical and Biochemical Assays for Screening Small Molecule Inhibitors Targeting Toxin-Ribosome Interactions. [PDF]

Toxins (Basel)
Bryan EJ, Vijayanand V, Li XP, McLaughlin JE, Pierce M, Dutta A, Tumer NE.   +6 more
europepmc   +1 more source