Results 161 to 170 of about 48,775 (245)

RiboSeq.Org: an integrated suite of resources for ribosome profiling data analysis and visualization. [PDF]

open access: yesNucleic Acids Res
Tierney JAS   +9 more
europepmc   +1 more source

Transcriptome and proteome analyses reveal divergent adaptive strategies in nasopharyngeal epithelial cells and nasopharyngeal carcinoma cells under ultra‐low background radiation

open access: yesDeep Underground Science and Engineering, EarlyView.
This study demonstrates that the ultra‐low background radiation environment in deep underground laboratories significantly inhibits the proliferation of both normal nasopharyngeal epithelial cells (HNEPC) and nasopharyngeal carcinoma cells (HNE‐1) cells, with malignant cells exhibiting higher sensitivity.
Yuhao Zou   +15 more
wiley   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

Transcriptomic analysis reveals distinct expression patterns in focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a common cause of drug‐resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response.
Shivani Sonawane   +20 more
wiley   +1 more source

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Extracellular vesicles derived from edible plants and edible fungi: Compositional characteristics, engineering strategies and biofunctions

open access: yesFood Biomacromolecules, EarlyView.
Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu   +6 more
wiley   +1 more source

Organ‐Resolved Host Proteomic and Post‐Translational Modification Landscapes in a Mouse Model of Talaromyces marneffei Infection

open access: yesiMetaMed, EarlyView.
We presented an organ‐resolved, multiple PTM remodeling atlas of systemic T. marneffei infection, integrating quantitative proteome, phosphoproteome, ubiquitinome, acetylome, and lactylome data across the liver, lung, and spleen. The atlas delineated organ‐specific PTM signatures and a functional convergence of divergent modification types on immune ...
Wudi Wei   +16 more
wiley   +1 more source

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

open access: yesiMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu   +9 more
wiley   +1 more source

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