Results 191 to 200 of about 48,775 (245)

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

A revised genome annotation of the model cyanobacterium Synechocystis based on start and stop codon-enriched ribosome profiling and proteogenomics

Hadjeras L, Krauspe V, Gelhausen R, Heiniger B, Spät P, Reimann V, Jaques G, Minges P, Bilger R, Gerstner M, Maček B, Ahrens CH, Backofen R, Sharma CM, Hess WR.   +14 more
europepmc   +1 more source

Correction to: Unraveling the small proteome of the plant symbiont <i>Sinorhizobium meliloti</i> by ribosome profiling and proteogenomics. [PDF]

Microlife
europepmc   +1 more source

RiboGraph: an interactive visualization system for ribosome profiling data at read length resolution. [PDF]

Bioinformatics
Chacko J, Ozadam H, Cenik C.
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Author Correction: Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling. [PDF]

Nat Commun
Bertrand L, Nelde A, Ramirez BC, Hatin I, Arbes H, François P, Demais S, Labaronne E, Decimo D, Guiguettaz L, Grégoire S, Bet A, Beauclair G, Gross A, Ziegler MC, Pereira M, Jeger-Madiot R, Verdier Y, Vinh J, Cardinaud S, Graff-Dubois S, Esclatine A, Gouttefangeas C, Altfeld M, Hocqueloux L, Samri A, Autran B, Lambotte O, Rammensee HG, Ricci EP, Walz J, Namy O, Moris A.   +32 more
europepmc   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

Ribosome profiling and single-cell RNA sequencing identify the unfolded protein response as a key regulator of pigeon lactation. [PDF]

Zool Res
Liu J, Liu SF, Mao HR, Jiang HX, Liu SB, Xu XF, Wu JT, Liu X, Zhang WT, Hu XL, Chen B.   +10 more
europepmc   +1 more source

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Small, EarlyView.
A phage‐free, microbial platform produces programmable circular ssDNA libraries that are enzymatically converted into DNA origami staple pools. Rolling‐circle replication generates sequence‐complex ssDNA with >99% fidelity, enabling assembly of DNA tiles and tubules and supporting nanostructure formation even in crude cellular lysates.
Ming Hung Yen, Mallikarjuna Reddy Kesama, Yancheng Du, Jong Hyun Choi, Kevin V. Solomon   +4 more
wiley   +1 more source