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TARM1 is a LILR family member that drives cell signalling via interactions with FcRγ. Here the authors show that TARM1 binds collagens to activate dendritic cells and thereby is an effector of inflammatory arthritis, plus provide a soluble TARM-Fc fusion
Rikio Yabe +10 more
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Antigens (Ags) with multivalent and repetitive structure elicit IgG production in a T-cell-independent manner. However, the mechanisms by which such T-cell-independent type-2 (TI-2) Ags induce IgG responses remain obscure.
Saori Fukao +3 more
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AbstractRibbing disease is a rare sclerosing dysplasia that involves long tubular bones, especially the tibia and femur. It occurs after puberty and is reported to be more common in women. In this article we describe how Ribbing disease can be differentiated from diseases like Engelmann-Camurati disease, van Buchem disease, Erdheim-Chester disease ...
Mukkada Philson +3 more
openaire +4 more sources
Identification of an anti-plant-virus molecule in Alpinia zerumbet
In plants, viral diseases are second only to fungal diseases in terms of occurrence, and cause substantial damage to agricultural crops. The aqueous extracts of shell ginger, Alpinia zerumbet exhibit inhibitory effects against virus infections in ...
Tadashi Hatanaka +4 more
doaj +1 more source
Multi-faceted regulation of IgE production and humoral memory formation
IgE antibodies play a protective role against parasites and environmental toxins by its strong effector functions. However, aberrant IgE production can contribute to the development of allergic disorders, and thus is tightly regulated.
Kei Haniuda, Daisuke Kitamura
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Clinical characteristics of patients with the hardware failure after surgical stabilization of rib fractures in Korea: a case series [PDF]
Purpose Surgical stabilization of rib fractures (SSRF) is widely used in patients with flail chests, and several studies have reported the efficacy of SSRF even in multiple rib fractures.
Na Hyeon Lee +9 more
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Objctive. To evaluate the analgesic efficacy of prolonged erector spinae fascial plane (ESFP) block in patients with multiple rib fractures.Material and methods. The study included 40 patients with multiple rib fractures.
V. H. Sharipova, I. V. Fokin
doaj +1 more source
Novel activity of Streptomyces aminopeptidase P
Streptomyces aminopeptidase P enzymes are proline-specific peptidases that belong to the peptidase M24 family. To evaluate the activity of a commercial Streptomyces aminopeptidase P, named ‘XPO DUET’, we performed three experiments involving degradation ...
Kun Wan +4 more
doaj +1 more source
Background and Aims: Inadequately managed pain due to multiple rib fractures (MRFs) can lead to atelectasis, pneumonia, prolonged ICU stay thereby leads to significant morbidity, morbidity and cost of treatment.
Sandeep Diwan, Abhijit Nair
doaj +1 more source
Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
Summary: The germinal center (GC) reaction is essential for long-lived humoral immunity. However, molecular requirements for the induction of Bcl6, the master regulator for GC B cell differentiation, remain unclear.
Kei Haniuda +2 more
doaj +1 more source

