Results 51 to 60 of about 240,402 (354)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Effect of Channel Orientation and Rib Pitch-to-Height Ratio on Pressure Drop in a Rotating Square Channel with Ribs on Two Opposite Surfaces

open access: yesInternational Journal of Rotating Machinery, 2005
The effect of channel orientation and rib pitch-to-height ratio on the pressure drop distribution in a rib-roughened channel is an important issue in turbine blade cooling. The present investigation is a study of the overall pressure drop distribution in
Prabhu S. V.   +2 more
doaj   +2 more sources

Reinforced concrete ribbed slabs with wide-beam

open access: yesRevista IBRACON de Estruturas e Materiais, 2018
Ribbed slabs have been widely used in buildings due to their many advantages, especially the decrease of concrete below the neutral line. This paper presents an experimental and computational study on ribbed slabs with wide-beam, two one-way slabs and ...
P. V. P. SACRAMENTO   +2 more
doaj   +2 more sources

Fracture of the Second Rib: An Indirect Sign of Serious Trauma Like Fracture of the First Rib?

open access: yesJournal of Chest Surgery, 2023
Background: The first 3 ribs are anatomically well-protected, shielded by the large thoracic muscles, the shoulder girdle, and the arm. A significant force is required to fracture these ribs; thus, such fractures suggest a high-energy trauma and are ...
Michail Tsimpinos   +4 more
doaj   +1 more source

Osteochondroma of rib

open access: yesPan African Medical Journal, 2022
Osteochondroma is also known as exostosis and is a benign bone tumour. It commonly presents in the first 3 decades of life with a male preponderance. The most common site for the development of these tumours is the metaphysis of long bones, with almost 30% of cases originating from the distal metaphysis of the femur.
openaire   +3 more sources

The biomechanical significance of bifurcated cervical ribs in apatosaurine sauropods

open access: yes, 2023
Bifurcated cervical ribs have evolved infrequently in dinosaurs. Previously documented examples include those in abelisaurid theropods, leptoceratopsid ceratopsians, and turiasaurian sauropods.
Taylor, Mike   +5 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

A case of severe type of cerebro-costo-mandibular syndrome [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2016
Introduction. Cerebro-costo-mandibular syndrome (CCMS) is a rare disorder, with only 75 cases described in the literature to date. CCMS is characterized by association of micrognathia and specific multiple rib defects.
Matić Aleksandra   +3 more
doaj   +1 more source

Variability of Child Rib Bone Hounsfield Units using in vivo Computed Tomography [PDF]

open access: yes, 2013
The variability assessment of the rib bone mechanical properties during the growth process is still missing. These properties could not be obtained in vivo on children.
SIDELKEIR, Zaki   +5 more
core  

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Home - About - Disclaimer - Privacy