Results 101 to 110 of about 61,264 (282)

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

open access: yesAdvanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang   +9 more
wiley   +1 more source

Çok Zayıf Hadis: Bir Mefhumun Geçmişten Günümüze Gelişim Seyri

open access: yesKocatepe İslami İlimler Dergisi
Hadis metodolojisinde sahih, hasen ve zayıf diye yapılan temel sınıflandırmalarda, zayıf olarak nitelenen hadislerin kapsadığı alan geniş bir çeşitliliği barındırmaktadır.
Halil İbrahim Turhan, Kadir Zeki
doaj   +1 more source

Rical tenkidinin doğuşu ve gelişmesi

open access: yes, 2020
The Hadith which is the second source of İslam after the Holy Qur'an has reached from beginning to nowadays by means of the Rawi (narrators). Almost in every area, especi-ally the authenticity of Hadith, the reliabilty of Rawii has a special importance. For this purpose, from the first century, Islamic scholars examined the Rawiis and if necessary
openaire   +1 more source

INTERACTION POTENTIAL FIELD BETWEEN A GEOMET-RICAL KINK AND A POINT DEFECT

open access: yesActa Physica Sinica, 1992
A vector expression of the dilatotion field of a segment of dislocation line was obtained with isotropic elasticity. The interaction potential field between a geometric kink, made of straight segments or a smooth curve of dislocation, and a point defect was thus obtained.
openaire   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

open access: yesAdvanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt   +14 more
wiley   +1 more source

Ahmed Zerrûk’un “el-Ucâle” Adlı Eseri: Tevbe Sûresi’nin 112. Âyetinin İşârî Yorumu ve Ricâlü’l-Gayb Meselesine Farklı Bir Bakış

open access: yesTasavvuf İlmi ve Akademik Araştırma Dergisi, 2020
Ahmed Zerrûk (ö. 899/1493), Fas’ta doğmuş, Cezayir, Tunus, Mısır, Mekke ve Libya gibi döneminin ilim merkezlerinden önemli ölçüde istifade etmiş büyük bir âlimdir.
Hamide Ulupınar
doaj  

Dynamics of polymer ejection from capsid

open access: yes, 2014
Polymer ejection from a capsid through a nanoscale pore is an important biological process with relevance to modern biotechnology. Here, we study generic capsid ejection using Langevin dynamics.
Kaski, K.   +3 more
core   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

open access: yesAdvanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang   +6 more
wiley   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

open access: yesAdvanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang   +6 more
wiley   +1 more source

THE STABILITY OF NONLINEAR DEFORMABLE CYLINDRICAL COMPOSITE SHELLS UNDER NON-UNIFORM LOADS

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2013
The numerical analysis results of flexible cylindrical shells stability in static unsymmet- rical loading cases are given in the article. Geometrically nonlinear shell theory relations were used in computational model development.
S I Trushin, E V Sysoeva, T A Zhuravleva
doaj  

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