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Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded. [PDF]
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Qin W+8 more
europepmc +2 more sources
Diagnostic approach to rickets: an Endocrine Society of Bengal (ESB) consensus statement [PDF]
Rickets, one of the leading causes of bony deformities and short stature, can be calciopenic (inciting event is defective intestinal calcium absorption) or phosphopenic (inciting event is phosphaturia). Early diagnosis and timely treatment of rickets are
Ajitesh Roy+28 more
doaj +2 more sources
Nutritional rickets and its associated factors among under-five children in Assela referral and teaching hospital, Ethiopia: a hospital based cross-sectional study design [PDF]
Background Nutritional rickets is a preventable skeletal disorder caused by deficiencies in vitamin D, calcium, or phosphate, leading to softening and weakening of bones.
Helen Abebe+8 more
doaj +2 more sources
A practical approach to diagnose and treat rickets [PDF]
Rickets is a disease of growing bone, before fusion of epiphyses. There is defective mineralization of cartilage matrix in the zone of provisional calcification caused either by nutritional vitamin D deficiency and/or low calcium intake or by non ...
Aditi Jaiman+3 more
doaj +1 more source
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi+5 more
wiley +1 more source
Clinical characteristics of vitamin D deficiency rickets in infants and preschool children [PDF]
Purpose : Vitamin D deficiency rickets is a significant public health problem that results from insufficient exposure to sunlight and inadequate vitamin D supplementation. The purpose of this study is to identify the clinical characteristics of vitamin D
Kyoung Huh+5 more
doaj +1 more source
Rickets-vitamin D deficiency and dependency
Rickets is an important problem even in countries with adequate sun exposure. The causes of rickets/osteomalacia are varied and include nutritional deficiency, especially poor dietary intake of vitamin D and calcium.
Manisha Sahay, Rakesh Sahay
doaj +1 more source
Ideology and disease identity : the politics of rickets, 1929-1982 [PDF]
How can we assess the reciprocal impacts of politics and medicine in the contemporary period? Using the example of rickets in twentieth century Britain, I will explore the ways in which a preventable, curable non-infectious disease came to have enormous ...
Apple+50 more
core +1 more source
Burosumab therapy in children with x-linked hypophosphatemia [PDF]
BACKGROUND X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities.
Boot, Annemieke M+13 more
core +2 more sources
Background There’s abundant sunshine in the tropics but severe rickets is still observed. Nutritional rickets is associated with an increased risk of acute lower respiratory infections.
Thereza Piloya+5 more
doaj +1 more source