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The Lancet, 2014
Rickets, historically referred to as "the English disease", is common worldwide. Absence of phosphate at the growth plate and mineralising bone surfaces due to inadequate vitamin D supply either from sunlight exposure or diet is the main cause. Inherited disorders causing hypophosphataemia have shown the intricacies of phosphate metabolism.
Charlotte Jane, Elder +1 more
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Rickets, historically referred to as "the English disease", is common worldwide. Absence of phosphate at the growth plate and mineralising bone surfaces due to inadequate vitamin D supply either from sunlight exposure or diet is the main cause. Inherited disorders causing hypophosphataemia have shown the intricacies of phosphate metabolism.
Charlotte Jane, Elder +1 more
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Hormone Research in Paediatrics, 2000
X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D<sub>3</sub> or 1α-hydroxyvitamin D<sub>3</sub> plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected
SAGGESE, GIUSEPPE, BARONCELLI GI
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X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D<sub>3</sub> or 1α-hydroxyvitamin D<sub>3</sub> plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected
SAGGESE, GIUSEPPE, BARONCELLI GI
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Pediatric Clinics of North America, 2019
Hypophosphatemic rickets, mostly of the X-linked dominant form caused by pathogenic variants of the PHEX gene, poses therapeutic challenges with consequences for growth and bone development and portends a high risk of fractions and poor bone healing, dental problems and nephrolithiasis/nephrocalcinosis.
Martin, Bitzan, Paul R, Goodyer
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Hypophosphatemic rickets, mostly of the X-linked dominant form caused by pathogenic variants of the PHEX gene, poses therapeutic challenges with consequences for growth and bone development and portends a high risk of fractions and poor bone healing, dental problems and nephrolithiasis/nephrocalcinosis.
Martin, Bitzan, Paul R, Goodyer
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Orthopaedic Nursing, 2004
Nutritional (vitamin D deficiency) rickets is now a rarity in the industrial world because of food fortification. Most cases result from hereditary inborn errors of vitamin D metabolism or end-organ unresponsiveness as is exemplified in this case of hypophosphatemic rickets.
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Nutritional (vitamin D deficiency) rickets is now a rarity in the industrial world because of food fortification. Most cases result from hereditary inborn errors of vitamin D metabolism or end-organ unresponsiveness as is exemplified in this case of hypophosphatemic rickets.
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Journal of Pediatric Orthopaedics, 1982
Rickets secondary to hepatobiliary disease is a rare condition; however, the skeletal manifestations are similar to simple nutritional rickets. These skeletal changes include epiphyseal plate abnormalities, pseudofractures, bowing of long bones, scoliosis, and fractures.
M E, Holda, J R, Ryan
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Rickets secondary to hepatobiliary disease is a rare condition; however, the skeletal manifestations are similar to simple nutritional rickets. These skeletal changes include epiphyseal plate abnormalities, pseudofractures, bowing of long bones, scoliosis, and fractures.
M E, Holda, J R, Ryan
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Journal of Pediatric Orthopaedics, 1986
Over a 2-year period, the Orthopaedic Service at the Cincinnati (OH) Children's Hospital Medical Center noted eight patients to present with unusual fractures and musculoskeletal problems due to nutritional rickets. All were black, had been breast-fed until 6-12 months of age, and were vegetarians.
S T, Jacobsen, C K, Hull, A H, Crawford
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Over a 2-year period, the Orthopaedic Service at the Cincinnati (OH) Children's Hospital Medical Center noted eight patients to present with unusual fractures and musculoskeletal problems due to nutritional rickets. All were black, had been breast-fed until 6-12 months of age, and were vegetarians.
S T, Jacobsen, C K, Hull, A H, Crawford
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X-linked hypophosphatemic rickets without ?rickets?
Skeletal Radiology, 1991Wrist and knee radiographs from children with X-linked hypophosphatemic rickets were analyzed and compared with those from normal children and children with established rickets to assess whether radiographically apparent rickets is a consistent abnormality in X-linked hypophosphatemia. The absence or presence of rickets was correctly identified in 94.8%
M J, Econs +8 more
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Trends in Endocrinology & Metabolism, 1991
Nutritional rickets was once felt to be a disease of the past. In recent years, dietary patterns and the prevalence of unsupplemented breast feeding has led to a mild resurgence in rickets. The cases presented show a wide spectrum of nutritional disease, illustrating the common risk factors, the usefulness of vitamin-D metabolite assays in making a ...
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Nutritional rickets was once felt to be a disease of the past. In recent years, dietary patterns and the prevalence of unsupplemented breast feeding has led to a mild resurgence in rickets. The cases presented show a wide spectrum of nutritional disease, illustrating the common risk factors, the usefulness of vitamin-D metabolite assays in making a ...
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American Journal of Diseases of Children, 1932
The development of methods for inducing rickets experimentally in animals has made it possible to study and compare the effect of different agents for the cure and prevention of rickets. In fact, our biologic method for testing antirachitic agents can be carried out with such a degree of preciseness as to approach closely a quantitative chemical ...
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The development of methods for inducing rickets experimentally in animals has made it possible to study and compare the effect of different agents for the cure and prevention of rickets. In fact, our biologic method for testing antirachitic agents can be carried out with such a degree of preciseness as to approach closely a quantitative chemical ...
openaire +2 more sources