Results 21 to 30 of about 57,538 (217)
Burosumab therapy in children with x-linked hypophosphatemia [PDF]
, 2018 BACKGROUND X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities.
Boot, Annemieke M +13 more
core +2 more sources
BMC Pediatrics, 2018 Background There’s abundant sunshine in the tropics but severe rickets is still observed. Nutritional rickets is associated with an increased risk of acute lower respiratory infections.
Thereza Piloya +5 more
doaj +1 more source
Clinical characteristics of vitamin D deficiency rickets in infants and preschool children [PDF]
Korean Journal of Pediatrics, 2010 Purpose : Vitamin D deficiency rickets is a significant public health problem that results from insufficient exposure to sunlight and inadequate vitamin D supplementation. The purpose of this study is to identify the clinical characteristics of vitamin D
Kyoung Huh +5 more
doaj +1 more source
A novel pathogenic mutation of the CYP27B1 gene in a patient with vitamin D-dependent rickets type 1: a case report [PDF]
, 2014 BACKGROUND: Rickets can occur due to Vitamin D deficiency or defects in its metabolism. Three rare genetic types of rickets with different alterations of genes have been reported, including: Vitamin D dependent rickets type 1, Vitamin D dependent rickets
Abdulrahman MH Al Nemri +7 more
core +1 more source
Validation of a novel scoring system for changes in skeletal manifestations of hypophosphatasia in newborns, infants, and children: The Radiographic Global Impression of Change scale [PDF]
, 2018 Hypophosphatasia (HPP) is the heritable metabolic disease characterized by impaired skeletal mineralization due to low activity of the tissue-nonspecific isoenzyme of alkaline phosphatase.
Fujita, Kenji P +4 more
core +2 more sources
Diagnostic approach to rickets: an Endocrine Society of Bengal (ESB) consensus statement [PDF]
Annals of Pediatric Endocrinology & MetabolismRickets, one of the leading causes of bony deformities and short stature, can be calciopenic (inciting event is defective intestinal calcium absorption) or phosphopenic (inciting event is phosphaturia). Early diagnosis and timely treatment of rickets are
Ajitesh Roy +28 more
doaj +1 more source
Indian Journal of Pediatrics, 2023 AbstractNutritional rickets, caused by vitamin D and/or calcium deficiency is by far the most common cause of rickets. In resource-limited settings, it is therefore not uncommon to treat rickets with vitamin D and calcium. If rickets fails to heal and/or if there is a family history of rickets, then refractory rickets should be considered as a ...
Amish Chinoy, Raja Padidela
openaire +2 more sources
Types and Clinical Profile of Rickets in a Tertiary Care Hospital
Bangabandhu Sheikh Mujib Medical University Journal, 2009 Background: There are different types of rickets. Rickets presents with various clinical signs and symptoms. Familial X linked hypophosphatamic rickets (XLHR) is reported to be the commonest one.
Shohela Akhter +4 more
doaj +1 more source
Temporary brittle bone disease:association with intracranial bleeding [PDF]
, 2013 We report 20 infants aged between 1 month and 6 months found to have subdural bleeding and also multiple unexplained fractures in a pattern similar to that described earlier as temporary brittle bone disease. Child abuse seemed unlikely as a cause of the
Ayoub +105 more
core +3 more sources
Indian Journal of Endocrinology and Metabolism, 2012 Hypophosphatemic rickets is a disorder of bone mineralization caused due to defects (inherited/acquired) in the renal handling of phosphorus. This group includes varied conditions, X-linked hypophosphatemic rickets being the most common inheritable form of rickets. The other common forms are autosomal dominant hypophosphatemic rickets and tumor-induced
Varsha S Jagtap +5 more
openaire +5 more sources