Results 81 to 90 of about 20,005 (252)

RC1339/APRc from Rickettsia conorii is a novel aspartic protease with properties of retropepsin-like enzymes. [PDF]

PLoS Pathogens, 2014
Members of the species Rickettsia are obligate intracellular, gram-negative, arthropod-borne pathogens of humans and other mammals. The life-threatening character of diseases caused by many Rickettsia species and the lack of reliable protective vaccine ...
Rui Cruz, Pitter Huesgen, Sean P Riley, Alexander Wlodawer, Carlos Faro, Christopher M Overall, Juan J Martinez, Isaura Simões   +7 more
doaj   +1 more source

Prevalence and risk factors for murine typhus, scrub typhus and spotted fever group rickettsioses among adolescent and adult patients presenting to Yangon General Hospital, Yangon, Myanmar

Tropical Medicine &International Health, Volume 30, Issue 9, Page 966-977, September 2025.
Abstract Objectives To inform patient management and disease prevention, we sought to estimate the prevalence of, and identify risk factors for, scrub typhus, murine typhus, and spotted fever group rickettsioses (SFGR) among febrile patients presenting to hospital in Myanmar.
Thomas R. Bowhay, Tin Ohn Myat, Win Thandar Oo, Hla Kye Mone, Katrina J. Sharples, Matthew T. Robinson, Mayfong Mayxay, Paul N. Newton, Stuart D. Blacksell, Ampai Tanganuchitcharnchai, James E. Ussher, David R. Murdoch, Wah Win Htike, John A. Crump   +13 more
wiley   +1 more source

Relevance of gamma interferon, tumor necrosis factor alpha, and interleukin-10 gene polymorphisms to susceptibility to Mediterranean spotted fever. [PDF]

, 2009
The acute phase of Mediterranean spotted fever (MSF) is characterized by dramatic changes in cytokine production patterns, clearly indicating their role in the immunomodulation of the response against the microorganism, and the differences in cytokine ...
Bellanca, F, CARUSO, Calogero, Cillari, E, FORTE, Giusi Irma, LIO, Domenico, MANSUETO, Pasquale, MANSUETO, Serafino, MILANO, Salvatore, MISIANO, Gabriella, RINI, Giovam Battista, Sanacore, M, SCOLA, Letizia, VACCARINO, Loredana, Vitale, G   +13 more
core   +2 more sources

The case of Mediterranean spotted fever of the traveler returned from Zambia

Ticks and Tick-Borne Diseases
We report the case of a traveler who returned from Zambia and was diagnosed with Mediterranean spotted fever (MSF), an infectious disease caused by Rickettsia conorii conorii. The patient presented to Sapporo City General Hospital with symptoms of fever,
Takahiro Ichikawa, Yongjin Qiu, Shuji Ando, Yuto Takeuchi, Atsushi Nagasaka   +4 more
doaj   +1 more source

Absence of antibodies to Rickettsia spp., Bartonella spp., Ehrlichia spp. and Coxiella burnetii in Tahiti, French Polynesia

, 2014
International audienceAbtractBackgroundIn the Pacific islands countries and territories, very little is known about the incidence of infectious diseases due to zoonotic pathogens.
Broult, Julien, Fournier, Pierre-Edouard, Musso, Didier, Parola, Philippe, Raoult, Didier   +4 more
core   +3 more sources

A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. [PDF]

, 2019
Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Ahyong, Vida, Berdan, Charles A, Burke, Thomas P, Nomura, Daniel K, Welch, Matthew D   +4 more
core   +2 more sources

Serological Survey on the Occurrence of Rickettsia spp., Neospora caninum, Bartonella henselae and Toxoplasma gondii in Cats from Tuscany (Central Italy)

Animals, 2021
Asymptomatic cats often harbor pathogens, some of which have not been largely investigated in feline populations. The aim of this study was to evaluate the occurrence of antibodies against Rickettsia conorii, Rickettsia felis, Rickettsia typhi, Neospora ...
Valentina Virginia Ebani, Simona Nardoni, Michela Maestrini, Stefania Perrucci, Francesca Mancianti   +4 more
doaj   +1 more source

Statins limit Rickettsia conorii infection in cells

International Journal of Antimicrobial Agents, 2008
Recent data suggest that statins may have a beneficial effect during sepsis. In this study, we tested the effect of lovastatin and pravastatin on the cellular culture of Rickettsia conorii using a quantitative plaque assay model associated with an original image analysis algorithm. Statins added at the time of infection did not modify plaque formation,
Botelho-Nevers, E., Rolain, J. M., Espinosa, L., /Raoult, Didier   +3 more
openaire   +4 more sources

Legionella pneumophila modulates the host cytoskeleton by an effector of transglutaminase activity

mLife, Volume 4, Issue 3, Page 232-248, June 2025.
Abstract The bacterial pathogen Legionella pneumophila delivers more than 330 effector proteins into host cells through its Dot/Icm type IV secretion system (T4SS) to facilitate its intracellular replication. A number of these effectors modulate organelle trafficking pathways to create a membrane‐bound niche called the Legionella‐containing vacuole ...
Yan Liu, Yao Liu, Zhao‐Qing Luo
wiley   +1 more source

Serological differentiation of antibodies against Rickettsia helvetica, R. raoultii, R. slovaca, R. monacensis and R. felis in dogs from Germany by a micro-immunofluorescent antibody test [PDF]

, 2015
Background Spotted Fever Group (SFG) Rickettsiae can cause febrile diseases with or without rash in humans worldwide. In Germany only limited data are available about their medical significance.
Dobler, Gerhard, Kohn, Barbara, Moritz, Andreas, Pachnicke, Stefan, Pfeffer, Martin, Silaghi, Cornelia, Wächter, Miriam, Wölfel, Silke   +7 more
core   +3 more sources