Genotyping Rickettsia prowazekii Isolates [PDF]
Emerging Infectious Diseases, 2008 We developed a typing method that can differentiate 8 strains of Rickettsia prowazekii into 7 genotypes. This method can be used to type and trace the origin of R. prowazekii isolated from samples collected during epidemics after a bioterrorism attack.
Yong Zhu +4 more
doaj +7 more sources
Establishment of a Replicating Plasmid in Rickettsia prowazekii [PDF]
PLoS ONE, 2012 Rickettsia prowazekii, the causative agent of epidemic typhus, grows only within the cytosol of eukaryotic host cells. This obligate intracellular lifestyle has restricted the genetic analysis of this pathogen and critical tools, such as replicating ...
David O Wood +2 more
exaly +7 more sources
Discovery of a Protective Rickettsia prowazekii Antigen Recognized by CD8+ T Cells, RP884, Using an In Vivo Screening Platform [PDF]
PLoS ONE, 2013 Rickettsia prowazekii has been tested for biological warfare due to the high mortality that it produces after aerosol transmission of very low numbers of rickettsiae.
Michal Gazi +2 more
exaly +6 more sources
Fluorescence Activated Cell Sorting of Rickettsia prowazekii-Infected Host Cells Based on Bacterial Burden and Early Detection of Fluorescent Rickettsial Transformants [PDF]
PLoS ONE, 2016 Rickettsia prowazekii, the causative agent of epidemic typhus, is an obligate intracellular bacterium that replicates only within the cytosol of a eukaryotic host cell.
Aimee M Tucker, David O Wood
exaly +6 more sources
Identification and Characterization of Novel Small RNAs in Rickettsia prowazekii [PDF]
Frontiers in Microbiology, 2016 Emerging evidence implicates a critically important role for bacterial small RNAs (sRNAs) as post-transcriptional regulators of physiology, metabolism, stress/adaptive responses, and virulence, but the roles of sRNAs in pathogenic Rickettsia species remain poorly understood.
Hema P Narra +2 more
exaly +6 more sources
Involvement of Pore Formation and Osmotic Lysis in the Rapid Killing of Gamma Interferon-Pretreated C166 Endothelial Cells by Rickettsia prowazekii [PDF]
Tropical Medicine and Infectious Disease, 2022 Rickettsia prowazekii, the bacterial cause of epidemic typhus in humans, proliferates mainly within the microvascular endothelial cells. Previous studies have shown that murine macrophage-like RAW264.7 cells are rapidly damaged if they are pretreated ...
Jenifer Turco
doaj +3 more sources
Improved Detection and Sequencing of Rickettsia spp. DNA in South African Wildlife [PDF]
Veterinary Medicine and ScienceBackground Rickettsia spp. are obligate intracellular bacteria of the spotted fever group (SFG), typhus group (TG) and transitional group, with diverse vectors and significant zoonotic potential.
Carlo Andrea Cossu +5 more
doaj +3 more sources
Analysis of convergent gene transcripts in the obligate intracellular bacterium Rickettsia prowazekii. [PDF]
PLoS ONE, 2011 Termination of transcription is an important component of bacterial gene expression. However, little is known concerning this process in the obligate intracellular pathogen and model for reductive evolution, Rickettsia prowazekii.
Andrew Woodard, David O Wood
doaj +3 more sources
The genome sequence of Rickettsia prowazekii and the origin of mitochondria [PDF]
Nature, 1998 We describe here the complete genome sequence (1,111,523 base pairs) of the obligate intracellular parasite Rickettsia prowazekii, the causative agent of epidemic typhus. This genome contains 834 protein-coding genes.
Alireza Zomorodipour +2 more
exaly +4 more sources
A chimeric disposition of the elongation factor genes in Rickettsia prowazekii [PDF]
Journal of Bacteriology, 1996 An exceptional disposition of the elongation factor genes is observed in Rickettsia prowazekii, in which there is only one tuf gene, which is distant from the lone firs gene, In contrast, the closely related bacterium Agrobacterium tumefaciens has the ...
Jamal, A +4 more
core +6 more sources