进化分析表明,与线粒体亲缘关系最近的原核生物是立克次体(Rickettsia prowazekii).搜索酿酒酵母(Saccharomyces cerevisia)线粒体蛋白转运系统的35个亚基在立克次体中的同源蛋白质,仅发现了5个同源蛋白,且它们只属于转运系统在线粒体外膜和基质上的模块,没有发现转运系统在膜间隙和内膜模块的同源蛋白.对大肠杆菌(Escherichiacoli K-12 MG1655)的分析也有类似的结果.因此线粒体蛋白转运系统应该不是直接起源于内共生的原核生物.
刘震 +4 more
doaj
Transcriptional profiling of Rickettsia prowazekii coding and non-coding transcripts during in vitro host-pathogen and vector-pathogen interactions. [PDF]
Schroeder CLC +6 more
europepmc +1 more source
La protéomique ouvre de nouvelles perspectives dans la caractérisation des facteurs de virulence des bactéries associées au bio-terrorisme. L électrophorèse en 2 dimensions (2-DE) est une des techniques les plus couramment utilisée permettant une ...
PELLETIER, Nicolas, LA SCOLA, Bernard
core
Molecular phylogeny and rearrangement of rRNA genes in Rickettsia species
It has previously been observed that Rickettsia prowazekii has an unusual arrangement of the rRNA genes. In this species, the three rRNA genes, 16S (rrs), 23S (rrl), and 5S (rrf), are not linked in the typical arrangements for bacteria.
Fuerst, P, +3 more
core
Innate immune responses to Rickettsia: emerging themes and contrasts between species. [PDF]
Ly N, Guzman AA, Engström P, Burke TP.
europepmc +1 more source
Targeting surface cell antigen 2 increases sensitivity of Rickettsia typhi detection. [PDF]
Phuklia W +8 more
europepmc +1 more source
Pseudogenes, junk DNA, and the dynamics of Rickettsia genomes
Studies of neutrally evolving sequences suggest that differences in eukaryotic genome sizes result from different rates of DNA loss. However, very few pseudogenes have been identified in microbial species, and the processes whereby genes and genomes ...
Andersson, Siv GE,, Andersson, Jan O,
core
Complete genomes of Rickettsia typhi reveal a clonal population. [PDF]
Keeratipusana C +11 more
europepmc +1 more source
Surveillance of vector-borne infections: Dogs as sentinel animals for <i>Orientia</i> and <i>Rickettsia</i> exposure in five regions in Chile. [PDF]
López-Silva P +7 more
europepmc +1 more source
A repetitive nucleotide insertion in the rplV gene is associated with in vitro resistance to azithromycin in Rickettsia typhi. [PDF]
Phuklia W +11 more
europepmc +1 more source

