Rickettsia rickettsii RoaM negatively regulates expression of a limited number of rickettsial genes [PDF]
Adam M. Nock+9 more
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In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin and pristinamycin [PDF]
In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin, pristinamycin, and the pristinamycin compounds, P1 and P2, were determined by a dye uptake assay and a plaque assay. The MICs were 1 microgram/ml for roxithromycin, 2 micrograms/ml for pristinamycin, greater than 256 micrograms/ml for P1, and 2 micrograms/ml for
M Drancourt, D Raoult
openaire +3 more sources
A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. [PDF]
Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Ahyong, Vida+4 more
core +2 more sources
Comparative growth of spotted fever group Rickettsia spp. strains in Vero cells
In Brazil, the spotted fever group (SFG) Rickettsia rickettsii and Rickettsia parkeri related species are the etiological agents of spotted fever rickettsiosis. However, the SFG, Rickettsia rhipicephali, that infects humans, has never been reported.
Arannadia Barbosa Silva+8 more
doaj +1 more source
The purpose of this study was to do a serological survey on three rickettsial species: Rickettsia rickettsii and Rickettsia parkeri, two species of the spotted fever group (SFG) that are considered to be great importance for public health; and Rickettsia
Lucianne Cardoso Neves+8 more
doaj +1 more source
Core-genome guided novel therapeutic targets identification and chimeric vaccine designing against Rickettsia rickettsii [PDF]
Fizza Arshad+7 more
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Production and characterization of monoclonal antibodies to Rickettsia rickettsii [PDF]
Five mouse ascitic fluids (MAFs) containing monoclonal antibody to Rickettsia rickettsii were produced from three original fusions by murine hybridoma technology. The five MAFs were fractionated and purified; each contained monoclonal antibody of the immunoglobulin G2a subclass.
J. V. Lange, David H. Walker
openaire +3 more sources
Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine
Rocky Mountain spotted fever (RMSF) is a rapidly progressive and often fatal tick-borne disease caused by Rickettsia rickettsii. Its discovery and characterization by Howard Ricketts has been hailed as a remarkable historical example of detection and ...
Yongli Xiao+5 more
doaj +1 more source
Serological evidence of Rickettsia in horses from a semi-arid Brazilian region
Brazilian spotted fever (BSF) is a common tick-borne disease caused by Rickettsia rickettsii. Horses are the primary hosts of the main vector, Amblyomma sculptum, and are considered efficient sentinels for circulation of Rickettsia. Therefore, the aim of
Ila Ferreira Farias+6 more
doaj +1 more source
Rickettsia rickettsii is the causative agent of Brazilian spotted fever (BSF), for which humans and dogs are both susceptible. Dogs are sentinels in serological surveys, however, canine disease is rarely reported.
Sabrina Destri Emmerick Campos+8 more
doaj +1 more source