Moonlighting in Rickettsiales: Expanding Virulence Landscape [PDF]
The order Rickettsiales includes species that cause a range of human diseases such as human granulocytic anaplasmosis (Anaplasma phagocytophilum), human monocytic ehrlichiosis (Ehrlichia chaffeensis), scrub typhus (Orientia tsutsugamushi), epidemic ...
Pedro Curto, Isaura Simões
exaly +6 more sources
Type 1 secretion system and effectors in Rickettsiales
Obligate intracellular bacteria in the order Rickettsiales are transmitted by arthropod vectors and cause life-threatening infections in humans and animals. While both type 1 and type 4 secretion systems (T1SS and T4SS) have been identified in this group,
Tian Luo, Jere W Mcbride
exaly +5 more sources
Host association and intracellularity evolved multiple times independently in the Rickettsiales [PDF]
The order Rickettsiales (Alphaproteobacteria) encompasses multiple diverse lineages of host-associated bacteria, including pathogens, reproductive manipulators, and mutualists.
Michele Castelli +8 more
doaj +6 more sources
tRNA signatures reveal a polyphyletic origin of SAR11 strains among alphaproteobacteria. [PDF]
Molecular phylogenetics and phylogenomics are subject to noise from horizontal gene transfer (HGT) and bias from convergence in macromolecular compositions.
Katherine C H Amrine +2 more
doaj +11 more sources
The order Rickettsiales in the class Alphaproteobacteria comprises vector-borne pathogens of both medical and veterinary importance. Ticks, as a group, are second only to mosquitoes as vectors of pathogens to humans, playing a critical role in the ...
Xiaojing Jin +9 more
exaly +3 more sources
BackgroundThe evolution of the Alphaproteobacteria and origin of the mitochondria are topics of considerable debate. Most studies have placed the mitochondria ancestor within the Rickettsiales order.
Mohammed-Amin Madoui +2 more
exaly +3 more sources
Microbial diversity of ticks and a novel typhus group Rickettsia species (Rickettsiales bacterium Ac37b) in Inner Mongolia, China [PDF]
Ticks can carry multiple pathogens, and Inner Mongolia’s animal husbandry provides excellent environmental conditions for ticks. This study characterized the microbiome of ticks from different geographical locations in Inner Mongolia; 905 Dermacentor ...
Su Si +11 more
doaj +2 more sources
Resistance of Wolbachia to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales [PDF]
Bacterial and eukaryotic dihydrofolate reductase (DHFR) enzymes are essential for DNA synthesis and are differentially sensitive to the competitive inhibitors trimethoprim and methotrexate.
Ann M. Fallon
doaj +2 more sources
Genotyping of ticks: first molecular report of Hyalomma asiaticum and molecular detection of tick-borne bacteria in ticks and blood from Khyber Pakhtunkhwa, Pakistan [PDF]
Multiple ticks (Acari: Ixodoidea) carrying Rickettsiales bacteria have significant importance for both human and animal health. Thus, the purpose of this work was to genetically analyze tick species and their associated Rickettsiales bacteria in animal ...
Muhammad Kashif Obaid +4 more
doaj +2 more sources
Genetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study [PDF]
Background Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunnan Province. Methods Between May 18,
Chun-Hong Du +19 more
doaj +2 more sources

