Moonlighting in Rickettsiales: Expanding Virulence Landscape
The order Rickettsiales includes species that cause a range of human diseases such as human granulocytic anaplasmosis (Anaplasma phagocytophilum), human monocytic ehrlichiosis (Ehrlichia chaffeensis), scrub typhus (Orientia tsutsugamushi), epidemic ...
Isaura Simões, Pedro Curto
exaly +4 more sources
BackgroundThe evolution of the Alphaproteobacteria and origin of the mitochondria are topics of considerable debate. Most studies have placed the mitochondria ancestor within the Rickettsiales order.
Didier Raoult +2 more
exaly +4 more sources
Resistance of Wolbachia to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales [PDF]
Bacterial and eukaryotic dihydrofolate reductase (DHFR) enzymes are essential for DNA synthesis and are differentially sensitive to the competitive inhibitors trimethoprim and methotrexate.
Ann M. Fallon
doaj +3 more sources
Host association and intracellularity evolved multiple times independently in the Rickettsiales [PDF]
The order Rickettsiales (Alphaproteobacteria) encompasses multiple diverse lineages of host-associated bacteria, including pathogens, reproductive manipulators, and mutualists.
Michele Castelli +8 more
doaj +3 more sources
Type 1 secretion system and effectors in Rickettsiales
Obligate intracellular bacteria in the order Rickettsiales are transmitted by arthropod vectors and cause life-threatening infections in humans and animals. While both type 1 and type 4 secretion systems (T1SS and T4SS) have been identified in this group,
Duc-Cuong Bui, Jere W McBride, Tian Luo
exaly +3 more sources
A targeted PCR approach for the detection of IOLA in canine infectious respiratory disease samples during an atypical CIRD outbreak in winter 2023 [PDF]
BackgroundDuring winter 2023, an atypical canine infectious respiratory disease (aCIRD) outbreak was associated with high case-fatality rates and poor antibiotic response.
Mahamudul Hasan +12 more
doaj +2 more sources
Genetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study [PDF]
Background Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunnan Province. Methods Between May 18,
Chun-Hong Du +19 more
doaj +2 more sources
Jellyfish blooms through the microbial lens: temporal changes, cross-species and Jellyfish-water comparisons [PDF]
Jellyfish blooms have significant ecological and economic impacts, yet the microbial communities associated with these blooms remain poorly understood, despite their potential influence on host fitness and microbial communities in the surrounding water ...
Noga Barak +4 more
doaj +2 more sources
The microbiome of a Pacific moon jellyfish Aurelia coerulea. [PDF]
The impact of microbiome in animal physiology is well appreciated, but characterization of animal-microbe symbiosis in marine environments remains a growing need.
Aki H Ohdera +5 more
doaj +2 more sources
Assembly and Comparison of Ca. Neoehrlichia mikurensis Genomes
Ca. Neoehrlichia mikurensis is widely prevalent in I. ricinus across Europe and has been associated with human disease. However, diagnostic modalities are limited, and much is still unknown about its biology.
Tal Azagi +6 more
doaj +1 more source

