Results 261 to 270 of about 1,000,205 (352)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

open access: yesAdvanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang   +12 more
wiley   +1 more source

Possible Extension of Inner Scleral Fibers Into the Peripapillary Sclera Detected by Polarization-Sensitive OCT. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Xiong J   +12 more
europepmc   +1 more source

Millimeter-Wave High-Gain Ridge Gap Beam Steerable Antenna for 5G wireless Networks

open access: green, 2018
Mohammadmahdi Farahani   +3 more
openalex   +2 more sources

Robust Smart Superhydrophobic Cilia

open access: yesAdvanced Science, EarlyView.
To date, ciliated surfaces cannot withstand mechanical damage because cilia/wires are inherently fragile. By aligning magneto‐responsive, flexible, superhydrophobic microwires on the sidewall of vertical frames, the frames act as armors to protect microwires from mechanical damage; when needed, the microwires re‐align uprightly under a magnet field to ...
Chuanqi Wei   +4 more
wiley   +1 more source

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