Results 71 to 80 of about 4,800 (298)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Empirical Assessments of the Type and Strength of Stream Fish Habitat Associations Can Advance Understanding of Functional Diversity and Promote Effective Conservation

Diversity
The ability to accurately quantify biodiversity is fundamental to understanding ecological trends, identifying drivers of declines, and selecting effective conservation options.
Sean M. Hitchman, Martha E. Mather, Joseph M. Smith   +2 more
doaj   +1 more source

The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images

BMC Bioinformatics, 2010
Background There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subcellular localization of proteins.
Riffle Michael, Davis Trisha N
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Portrait of Florence Riffle

, 1920
Portrait of Florence May Riffle, Pacific University Class of 1928.[back] Florence M. Riffle/students and alumni Q -

core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Disentangling small dam impacts: macroinvertebrate metrics reveal local stressors in degraded agricultural streams

Journal of Freshwater Ecology
Agricultural land use and dams present prevalent, interacting stressors on freshwater ecosystems across Europe and globally. This study assessed the efficacy of established, taxonomy-based macroinvertebrate metrics for detecting localized dam impacts ...
Peter E. Carlson
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Turbulence structures in isolated pool-riffle units [PDF]

, 2019
The macroscale morphology of a river has significant effects on sediment transport, flow pattern, bed stability, and ecosystem function. Pools and riffles, which are respectively the deeper and shallower parts of the bed, are a common morphology that is ...
Dashtpeyma, Hamed
core  

Sediment routing hypothesis for pool-riffle maintenance

, 2013
This paper provides comprehensive evidence that sediment routing around pools is a key mechanism for pool-riffle maintenance in sinuous upland gravel-bed streams.
Milan, David J.
core   +1 more source