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Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice. [PDF]

PLoS ONE, 2018
Rift Valley fever (RVF) in humans is usually mild, but, in a subset of cases, can progress to severe hepatic and neurological disease. Rodent models of RVF generally develop acute severe clinical disease.
Jessica R Spengler, Anita K McElroy, Jessica R Harmon, JoAnn D Coleman-McCray, Stephen R Welch, James G Keck, Stuart T Nichol, Christina F Spiropoulou   +7 more
doaj   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, Volume 101, Issue 4, Page 1779-1792, August 2026.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source

Mycoplasma Contamination Alters the Expression Profile of Pro‐Inflammatory Cytokines by Human Innate Immune Cells

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The impact of Mycoplasma contaminations on in vitro test systems has been extensively discussed and in vitro studies have demonstrated various effects on the physiology of the contaminated cell line. Thus far, little is known about the effect of biologically active substances, such as viruses produced in contaminated cell lines on primary ...
Patricia Gogesch, Stefanie Kronhart, Marc A. Niles, Georg Kochs, Zoe Waibler, Martina Anzaghe   +5 more
wiley   +1 more source

Computer-Selected Antiviral Compounds: Assessing In Vitro Efficacies against Rift Valley Fever Virus

Viruses
Rift Valley fever is a zoonotic viral disease transmitted by mosquitoes, impacting both humans and livestock. Currently, there are no approved vaccines or antiviral treatments for humans.
Cigdem Alkan, Terrence O’Brien, Victor Kenyon, Tetsuro Ikegami   +3 more
doaj   +1 more source

Threshold Dynamics in a Periodic Three-Patch Rift Valley Fever Virus Transmission Model

Complexity, 2019
This paper investigates a three-patch Rift Valley fever virus transmission model with periodic coefficients. The basic reproduction number Ri0i=1,2,3 is calculated for the model by using the next infection operator method. The threshold conditions on the
Buyu Wen, Zhidong Teng, Wenlin Liu
doaj   +1 more source

Potential of Using Capripoxvirus Vectored Vaccines Against Arboviruses in Sheep, Goats, and Cattle

Frontiers in Veterinary Science, 2019
The genus capripoxvirus consists of sheeppox virus, goatpox virus, and lumpy skin disease virus, which affect sheep, goats, and cattle, respectively. Together capripoxviruses cause significant economic losses to the sheep, goat, and cattle industry where
Mahder Teffera, Mahder Teffera, Shawn Babiuk, Shawn Babiuk   +3 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Addressing Climate Driven Vector‐Borne Disease in West Africa

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Vector‐borne diseases (VBDs) pose a significant public health threat in West Africa, contributing to substantial morbidity and mortality, particularly among vulnerable populations. This region is highly susceptible to the effects of climate change due to its geographical location, dependence on rain‐fed agriculture, and fragile ...
Majani Edward, Oladipupo Iyanu Roseline, Emmanuel Victor, Oladeji Yinmi Gabriel   +3 more
wiley   +1 more source

Rift Valley fever: a review [PDF]

Microbiology Australia, 2020
Rift Valley fever (RVF) is a mosquito-borne viral disease, principally of ruminants, that is endemic to Africa. The causative Phlebovirus, Rift Valley fever virus (RVFV), has a broad host range and, as such, also infects humans to cause primarily a self ...
Petrus Jansen van Vuren, John Bingham
doaj  

Community Awareness, Knowledge, Attitudes, and Perceptions Toward Viral Disease Outbreaks in Dar es Salaam, Tanzania

Public Health Challenges, Volume 5, Issue 2, June 2026.
High awareness of viral outbreaks in Dar es Salaam coexists with critical knowledge gaps, stigma, and vaccine hesitancy driven by trust and safety concerns. Targeted myth correction, anti‐stigma initiatives, and strategic digital health communication are essential to strengthen community preparedness and outbreak response.
Mohammed Elmogiera Fadlallh Elsayed, Emmanuel J. Magandi, Sima Rugarabamu   +2 more
wiley   +1 more source