Results 141 to 150 of about 49,976 (250)

Age‐related loss of hysteresis in the spontaneous vascular sympathetic baroreflex is associated with altered neural rather than mechanical control

open access: yesExperimental Physiology, EarlyView.
Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes   +5 more
wiley   +1 more source

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas   +3 more
wiley   +1 more source

Sedentary ageing remodels the structure–function relationships that underlie calcium signalling at super‐resolution scales in the heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Illustration of calcium spark function and ryanodine receptor (RyR) structure within a sedentary model of ageing. Upon sympathetic stimulation from 1 µM isoprenaline a linear response to calcium spark morphology occurred, accompanied by a biphasic progression of RyR remodelling across age.
Miriam E. Hurley   +3 more
wiley   +1 more source

Norwood-I in a hypoplastic left heart variant and right aortic arch. [PDF]

open access: yesInteract Cardiovasc Thorac Surg, 2021
Amodeo A   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy