Results 61 to 70 of about 94,704 (297)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Right bundle branch block pattern in right ventricular endocardial pacing: A needless concern?

Heart India, 2013
Right ventricular (RV) endocardial pacing in permanent pacemaker implantation usually yields a left bundle branch block (LBBB) pattern in surface electrocardiogram (ECG).
Mangalachulli Pottammal Ranjith, Kalathingathodika Sajeer, Peringadan Gopalan Nithin, Vellani Haridasan, Gopalan Nair Rajesh, Cicy Bastian, Chakanalil Govindan Sajeev, Mangalath Narayanan Krishnan   +7 more
doaj   +1 more source

Prognostic Significance of Right Bundle Branch Block for Patients with Acute Myocardial Infarction: A Systematic Review and Meta-Analysis

Medical Science Monitor, 2016
Background The aim of the current meta-analysis was to assess the effect of right bundle branch block (RBBB) on mortality outcome in patients with acute myocardial infarction (AMI).
L. Xiang, Anyuan Zhong, Tao You, Jianchang Chen, Wei-ting Xu, M. Shi   +5 more
semanticscholar   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia [PDF]

, 2005
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo, Mazur, Alexander, Strasberg, Boris   +2 more
core   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Absent right bundle branch block: Is it a clue of pre-excitation in Ebstein's anomaly?

Indian Heart Journal, 2016
A 14-year-old male with a history of symptomatic tachycardia was referred for ablation. Sinus rhythm electrocardiogram was not showing any pre-excitation.
Pranil Bhalchandra Gangurde, Abhay Tidake, Hetan Shah, Ajay Mahajan, Yash Lokhandwala, Pratap Nathani   +5 more
doaj   +1 more source

Clinical characteristics and the severity of coronary atherosclerosis of different subtypes of bundle‐branch block

Annals of Noninvasive Electrocardiology, 2022
Background Right bundle‐branch block (RBBB) and left bundle‐branch block (LBBB) play a role in the pathogenesis and progression of coronary artery disease (CAD).
Tongjian Zhu, Mingxian Chen, Wei Hu, Benfang Wang, Hong Jiang   +4 more
doaj   +1 more source

Blok obu odnóg pęczka Hisa w przebiegu leczenia amitriptyliną [PDF]

, 2013
A 57 year-old man treated with amitriptyline was admitted because of several episodes of syncope. In ECG, the incompleteleft bundle branch block was masked by the complete right bundle branch block and left anterior fascicular ...
Foryś, Mariusz, Kramarz, Elżbieta
core   +2 more sources