Results 31 to 40 of about 188 (168)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Smarandache semirings, semifields, and semivector spaces [PDF]

open access: yes, 2002
Smarandache notions, which can be undoubtedly characterized as interesting mathematics, has the capacity of being utilized to analyse, study and introduce, naturally, the concepts of several structures by means of extension or identification as a ...
Vasantha, Kandasamy
core   +1 more source

Weak polynomial identities and their applications [PDF]

open access: yes, 2021
summary:Let $R$ be an associative algebra over a field $K$ generated by a vector subspace $V$. The polynomial $f(x_1,\ldots ,x_n)$ of the free associative algebra $K\langle x_1,x_2,\ldots \rangle $ is a weak polynomial identity for the pair $(R,V)$ if it
Drensky, Vesselin
core   +1 more source

Small-size ring coupler design method based on fully distributed composite right/left-handed approach

open access: yesElectronics Letters, 2012
A new method to design a small-size ring coupler is proposed, showing that the coupler may be seen as consisting of fully distributed composite right/left-handed phase shifters. A 3 dB ring coupler is designed by using the proposed method. The coupler is analysed numerically and then experimentally characterised.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A note on the structure of distributive rings

open access: yes, 2015
In this paper we prove that a prime ring which is both left and right distributive and has the Jacobson radical completely prime is a pullback of a prime chain ring and a Jacobson semisimple left and right distributive domain.
Ferrero, M, Paques, A
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Isotopy and geotopy for ternary rings of projective planes

open access: yes, 2008
We investigate the question of when two ternary rings coordinatize the same finite projective plane. Necessary and sufficient conditions are obtained for right quasifields and for right distributive linear rings whose multiplicative loop is a ...
Aschbacher, Michael
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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