Results 191 to 200 of about 2,706,400 (292)

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Right Infectious Cavernous Sinus Thrombosis Complicated by Multiple Cerebrovascular Events in the Right Hemisphere. [PDF]

Cureus
Kubota K, Matsubayashi T, Aizawa Y, Furuki M, Obayashi M.   +4 more
europepmc   +1 more source

Cavity‐Compatible Light Extraction in Top‐Emitting Microcavity OLEDs via a Gentle Internal Corrugation Layer and Resonance‐Matched Narrowband Emission

Advanced Science, EarlyView.
A gentle internal corrugation layer conformally reshapes the microcavity OLED stack, redistributing confined optical power toward extractable channels while preserving cavity‐controlled emission. Combined with optical clear resin and a resonance‐matched narrowband pTSF emissive system, this cavity‐compatible architecture delivers an external quantum ...
Young Rok Kim, Ajay Nimbalkar, Min Chul Suh   +2 more
wiley   +1 more source

Effects of robot assisted mirror therapy on motor function and cortical activation in patients with right hemisphere damage. [PDF]

Sci Rep
Wei Y, Wu L, Huang F, Fang R, Liu J, Liu L, Wang Y.   +6 more
europepmc   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source

Mechanistic Insights Into Instability From Single Void Dynamics at the Lithium Metal‐Solid Electrolyte Interface

Advanced Science, EarlyView.
Void morphology at the lithium metal‐solid electrolyte contact governs electrochemical contact stability in all‐solid‐state batteries. This work resolves the competing roles of electrochemical reaction, bulk vacancy diffusion, and distinct surface diffusion pathways in dictating the size and morphology evolution of a single void and its transition to a
Sourim Banerjee, Bairav S. Vishnugopi, Guang Lin, Partha P. Mukherjee   +3 more
wiley   +1 more source

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

Advanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding, Haibiao Xu, Cen Liu, Yangyin Ding, Shuai Wang, Jun Yin, Tao Fu, Xiao Jiang, Yuning Chen, Hui Luo, Rui Li, Zhengxin Chen, Huibo Wang   +12 more
wiley   +1 more source

Right hemisphere engagement in language abilities in older adults: indication of compensation rather than decline. [PDF]

Front Aging
Solomons D, Rodriguez-Fernandez M, Mery-Muñoz F, Arraño-Carrasco L, Toloza-Ramirez D, Sahli-Costabal F, Mendez-Orellana C.   +6 more
europepmc   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

Elucidating White Matter Contributions to the Cognitive Architecture of Affective Prosody Recognition: Evidence from Right Hemisphere Stroke. [PDF]

Brain Sci
Jackson MS, Uchida Y, Sheppard SM, Oishi K, Crainiceanu C, Hillis AE, Durfee AZ.   +6 more
europepmc   +1 more source