Results 21 to 30 of about 662 (146)
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk +5 more
wiley +1 more source
An Ocular Surface‐Targeting Nucleic Acid Hydrogel for Efficient Dry Eye Disease Treatment
A self‐assembled nucleic acid hydrogel modified with mucin‐1 (MUC1) aptamer is developed, which can actively target the mucin layer on the ocular surface and significantly extend its retention time after distillation. Inside the hydrogel, therapeutic siRNA is embedded and can effectively silence the inflammation gene expression, subsequently restoring ...
Yuhe Liu +12 more
wiley +1 more source
ABSTRACT This study examines gendered work–family balance (WFB) experiences among dual‐career academic couples at U.S. research‐intensive universities. By comparing faculty couples who shared the same or similar professional and family contexts, the study explores how gendered demands, challenges, resources, and strategies shaped distinct WFB outcomes.
Kyung Nam Kim, Shinhee Jeong
wiley +1 more source
Body weight in autism spectrum disorder: A systematic review and meta‐analysis
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz +8 more
wiley +1 more source
Precision Restoration to Minimize Soil Loss in a Watershed in the Atlantic Forest Domain
ABSTRACT The Turvo River Watershed, located in the Zona da Mata region of Minas Gerais and part of the Doce River Basin, faces serious problems of erosion and soil degradation, which compromise and reduce the quality of local water resources. Given this scenario, it is essential to implement environmental recovery strategies that prioritize the ...
Rodrigo Nobre Santana +6 more
wiley +1 more source
Multi‐Agent Reinforcement Learning for Joint Police Patrol and Dispatch
ABSTRACT Police patrol units need to split their time between performing preventive patrol and being dispatched to serve emergency incidents. In the existing literature, patrol and dispatch decisions are often studied separately. We consider joint optimization of these two decisions to improve police operations efficiency and reduce response time to ...
Matthew Repasky, He Wang, Yao Xie
wiley +1 more source
Imaging spectroscopy enables large‐scale biodiversity assessment, yet spectral diversity metrics are scale dependent. Across 15 NEON ecosystems, we find that spectral richness increases sub‐linearly from 3600 m2 to 4 km2, whereas spectral divergence shows weak or inconsistent scaling with area, underscoring the importance of scale‐aware interpretation ...
Meghan T. Hayden +8 more
wiley +1 more source
With a Great Story Comes Great Responsibility: Role of Narrative in Leadership Development
ABSTRACT Comic books reside uniquely within American culture. Historians have contended comics are more than just sequential artwork mixed with engaging stories, but rather, a framework by which the generations make sense of who they are. These stories are a reflection of cultural conscience; a lens through which we can view the world and a mirror ...
Sean Connable
wiley +1 more source
Influence of heme and pH on the oligomeric states of Brucella melitensis bacterioferritin
The oligomerization of B. melitensis bacterioferritin (BmBfr) was studied using X‐ray crystallography, size‐exclusion chromatography and thermal shift analysis. These techniques allowed the characterization of both apo and holo BmBfr, highlighting the impact of heme and pH on the oligomerization mechanism.Bacterioferritin from Brucella melitensis ...
Tanguy Scaillet +2 more
wiley +1 more source
ABSTRACT Tracing the early adoption of computer gang databases by the Los Angeles County Sheriff's Department and the Los Angeles Police Department in the 1980s to the deployment of computationally‐assisted surveillance during the Vietnam War, this paper uses a genealogical approach to compare surveillance technologies developed across the arc of ...
Christina Hughes
wiley +1 more source

