Results 141 to 150 of about 868,255 (306)

AFP Stimulates Glucose Metabolic Reprogramming Contributing to Hepatocellular Carcinoma Resist Sorafenib Through Activating PI3K/AKT Signalling Pathway. [PDF]

J Cell Mol Med
Zhou Y, Feng S, Chen Y, Lin B, Li W, Dong X, Liu K, Yin Q, Li M, Zhu M.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Learning from a pitfall: Atrial septostomy in LV failure under VA-ECMO for pulmonary hypertension. [PDF]

J Extra Corpor Technol
Wirth C, De Normandie P, Hascoet S, Fadel E, Stephan F.   +4 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Spinoza e o Direito de Resistência

, 2014
This work aims at the analysis of the Spinoza’s concept of right of resistance. At the beginning of this work is developed an investigation about the historic and theoretical circumstances that influenced the Spinoza’s reflections about the right of ...
de Guimaraens, Francisco, Rocha, Maurício   +1 more
core  

Desobediência civil no Direito brasileiro: o direito de resistência de associações civis na produção de canabinoides para uso terapêutico no Brasil

This article evaluates the exercise of the right of resistance by civil associations in the face of the prohibition of the commercialization of Cannabis sativa in Brazil, harming the production of cannabinoids for medicinal use, with the objective of ...
Themudo, Tiago Seixas, Paz, Victor Vasconcelos Rodrigues, Melo, Álisson   +2 more
core   +1 more source

Generation of new cisgenic apple lines resistant to either apple scab or fire blight. [PDF]

Planta
Schlathölter I, Flachowsky H, Studer B, Schouten HJ, Patocchi A, Broggini GAL.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Machine learning for prediction of key haemodynamic parameters in pulmonary arterial hypertension. [PDF]

Eur Heart J Digit Health
Kramer T, Weis H, Kramer M, Baldus S, Rosenkranz S, Spinler S.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source