Results 101 to 110 of about 794,618 (307)

'Notice and staydown' and social media: amending Article 13 of the Proposed Directive on Copyright [PDF]

open access: yes, 2018
© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits ...
Romero Moreno, Felipe
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Court interpreting in Italy. The daily violation of a fundamental human right [PDF]

open access: yes, 2012
The paper analyses the situation of court interpreting in Italy and examines three cases of blatant violation of the defendants’ right to a fair ...
Garwood, Christopher John
core   +1 more source

Incompatibility of the Digital Economy Act 2010 subscriber appeal process provisions with Article 6 of the ECHR [PDF]

open access: yes, 2014
This is the accepted manuscript of an article published by Taylor & Francis in International Review of Law, Computers and Technology on 10 January 2014. The version of record [Romero-Moreno, F.
Felipe Romero Moreno   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The right to a fair trial and a modern civil procedure model

open access: yesПроблеми Законності, 2018
In the article the author tries to depart from the previous conventional approach according to which the model of civil procedure is characterized only as adversarial one.
Наталія Юріївна Сaкара
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Particular European Standards of Guaranteeing the Right to a Fair Trial in the Context of International Armed Conflict

open access: yesТеорія і практика правознавства
The relevance of the research topic is due to at least several factors. Firstly, according to the analysis of the case law of the European Court of Human Rights, as well as annual reports on this issue, improper compliance with the standards of ensuring
Iryna Krytska
doaj   +1 more source

Mental Illness and Self-Representation: Faretta, Godinez and Edwards [PDF]

open access: yes, 2009
In the recent decision of Indiana v. Edwards the Supreme Court held that the right to represent oneself may be denied to defendants who are competent to stand trial if they "still suffer from severe mental illness to the point where they are not ...
Slobogin, Christopher
core   +2 more sources

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