Results 61 to 70 of about 740,145 (358)
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
The purpose of this research is to analyze the causes of non-implementation of witness protection laws in Pakistan and their effects on the right of a fair trial.
A. Uddin, Liaquat Ali
semanticscholar +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
International experience in legal support of freedom of speech on the Internet
The relevance of the studied subject lies in the fact that freedom of speech is a fundamental human right that should be ensured at the legislative level.
L. Golovko, V. Ladychenko, O. Kapplová
doaj +1 more source
The Fairness of a Fair Trial: Not Guilty Pleas and the Right to Effective Assistance of Counsel [PDF]
The pervasiveness of plea bargaining in our modern justice system has led too many courts to conclude that the Sixth Amendment right to effective assistance of counsel applies to not guilty pleas. This Note argues that, although the United States Supreme
Tinmouth, Leigh
core
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Розумний строк судового розгляду та концепція керування часом судового розгляду
Постановка проблеми. Розумний строк судового розгляду є невід’ємним елементом права на справедливий судовий розгляд, закріпленого у п. 1 ст. 6 Європейської конвенції про захист прав людини та основоположних свобод.
Тетяна Андріївна Цувіна
doaj +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
The paper examines the application of Artificial Intelligence systems in the judicial environments. It provides an outline of a typology of different algorithms applicable in judicial environments depending on judicial decision-making stage.
Donatas Murauskas
doaj +1 more source