Results 71 to 80 of about 792,883 (356)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Reflections on reform of Croatian criminal procedure through the perspective of the defendant's right to a fair trial [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2014
Croatian criminal procedure has been significantly reformed in the latest, fifth legislative amendment passed in November 2013, which was supposed to fully implement the decision of the Croatian Constitutional Court of 19 July 2012 and harmonize the ...
Ivičević-Karas Elizabeta
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Right to a Fair Trial and the Free Movement of Civil Judgments

open access: yesCroatian Yearbook of European Law and Policy, 2010
This paper analyses the role and function of the right to a fair trial in Brussels I. Particular emphasis will be placed on how the European Court of Justice balances the right to a fair trial against the free movement of judgments. This question will be
Jan-Jaap Kuipers
doaj   +1 more source

Giving effect to young people’s right to effectively participate in criminal proceedings [PDF]

open access: yes, 2016
Article 6 of the European Convention on Human Rights, guarantees the right to a fair trial, including the right of all defendants to participate effectively in their trial. Although psychiatrists and psychologists frequently report that defendants in the
Arthur, Raymond
core   +1 more source

Revitalisasi Keberpihakan Profesi Advokat terhadap Klien yang Tidak Mampu [PDF]

open access: yes, 2012
Revitalizing the role of advocate is very urgent now, so that its position is still worth mentioning as one of the elements of law enforcement, even as the front line in providing human rights protection, especially for people who can not afford to ...
Nurudin, A. (Agus)
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Effective Court Administration and Professionalism of Judges as Necessary Factors Safeguarding the Mother of Justice – The Right to a Fair Trial

open access: yesInternational Journal for Court Administration, 2019
One of the fundamental human rights and the rights of nations is the Right to a fair trial. A legal paradox is that immense violations of this right have been declared worldwide for many years despite the significance of this right and the fact that it ...
Mindaugas Simonis
doaj   +1 more source

Balancing fairness to victims, society and defendants in the cross-examination of vulnerable witnesses: an impossible triangulation? [PDF]

open access: yes, 2014
This article argues that direct cross-examination of vulnerable witnesses should be removed from Australian trials, to reduce any illegitimate advantage to the defendant.
David Plater   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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