Results 161 to 170 of about 1,765,259 (347)

Natural Right to Grow and Die in the Form of Wholeness: A Philosophical Interpretation of the Ontological Status of Brain-dead Children [PDF]

, 2010
Masahiro Morioka
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Un dilema ético actual: ¿Ensañamiento terapéutico o adecuación del esfuerzo terapéutico?

Revista Médica Electrónica
La medicina está estrechamente relacionada con el uso cada vez más de modernas tecnologías, muy sofisticadas y poderosas, que ofrecen posibilidades sin precedentes, en cuanto a la prolongación de la vida.
Gilberto Lázaro Betancourt Reyes
doaj  

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Taking Europe to Its Extremes : Examining Cueing Effects of Right-Wing Populist Parties on Public Opinion Regarding European Integration [PDF]

, 2005
In this article we examine the role of right-wing parties in framing and mobilizing national identity against European integration. Using a multi-level analysis and combining individual-level and contextual data, we analyze public support for European ...
Edwards, Erica, Netjes, Catherine E.
core   +1 more source

Targeting the metabolic flexibility of cancer cells: Straighten up and die right [PDF]

, 2011
Isaac Marin‐Valencia, Ralph J. DeBerardinis   +1 more
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

What Kind of a Right is the ‘Right to Die’?

European Journal of Mental Health, 2009
Constance E. Putnam
doaj   +1 more source

Right to die case goes to House of Lords

, 2001
C. Dyer
openalex   +2 more sources

Rechte Parteien im Europäischen Parlament und der Beitritt Südosteuropas – eine Gefahr für die europäische Demokratie? / Right-wing Parties in the European Parliament and the Accession of Southeastern Europe: a Danger for European Democracy? [PDF]

, 2012
Olaf Leiße
openalex   +1 more source