Results 71 to 80 of about 4,344,934 (307)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Education as a non-negotiable right: subjects in the countryside, trajectories and (im)probable futures

open access: yesRevista Brasileira de Educação do Campo
The article presents reflections on the right to education in Brazil, taking into account the results of the research entitled “Rural subjects and the right to education: trajectories, challenges and (im)probable fruits”.
Mariana Martins de Meireles   +1 more
doaj   +1 more source

Boko Haram Terrorism and a Threat to Right to Education

open access: yesHasanuddin Law Review, 2020
The government shall direct its policy towards giving to the citizens equal and adequate educational opportunities at all levels. Although, not classified as a fundamental right, this constitutional prescription remains at the forefront of the basic ...
Ayobami Samson Joshua
doaj   +1 more source

The Obsolescence of San Antonio v. Rodriguez in the Wake of the Federal Government’s Quest To Leave No Child Behind [PDF]

open access: yes, 2012
Since the mid-1950s, a sea change in public education has taken place. Public education—a policy concern traditionally reserved to the states—has become a core concern of the federal government.
Boyce, Sarah G.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

“Access Denied” – Interpreting the Digital Divide by Examining the Right of Prisoners to Access the Internet in the Case Law of the European Court of Human Rights

open access: yesBaltic Journal of Law & Politics
The present paper aims to investigate prisoners’ rights to use and access the Internet, focusing on the jurisprudence of the European Court of Human Rights (ECtHR).
Lendvai Gergely Ferenc   +1 more
doaj   +1 more source

Legal problems of ensuring equal conditions for realization the constitutional right to education

open access: yesПравоприменение, 2018
The subject of the paper is legal conditions for realization the constitutional right to education.The purpose of the paper is to confirm or disprove the hypothesis that legal measures of realization of the right to education that are used in developed ...
A. Matnenko
doaj   +1 more source

Who Owns the Soul of the Child?: An Essay on Religious Parenting Rights and the Enfranchisement of the Child [PDF]

open access: yes, 2012
At common law, and (for most of the nation\u27s history) under state statutory regimes, the authority of the parent to direct the child\u27s upbringing was a matter of duty, not right, and chief among parental obligations was the duty to provide the ...
Shulman, Jeffrey
core   +1 more source

Education Rights and Wrongs: Publicly Funded Vouchers, State Consitutions, and Education Death Spirals [PDF]

open access: yes, 2014
A response to Julie F. Mead, The Right to an Education or the Right to Shop for Schooling: Examining Voucher Programs in Relation to State Constitutional Guarantees, 42 FORDHAM URB. L.J. 703 (2015)
Heise, Michael
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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